Cervical cancer mortality has been reduced in Australia because of effective screening programs, but there are still about 800 new cases... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2008
• February 2008

The ANZCHOG-BN was developed to improve and streamline access to high quality pediatric and adolescent/young adult cancer biospecimens for cancer research ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

To identify Helicobacter pylori and related oncogenic and virulent proteins in patients with gingivitis, periodontitis, oral cancer and gastric cancer. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Skin cancer prevention efforts in Australia have increasingly incorporated a focus on protection during incidental sun exposure. This complements the long-present messages promoting protection in high-risk settings and avoidance of acute intense bouts of sun exposure. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

There is a strong theoretical rationale for combining checkpoint blockade with cytotoxic chemotherapy in pleural mesothelioma and other cancers. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Mesothelioma is a cancer that typically originates in the pleura of the lungs. It rapidly invades the surrounding tissues, causing pain and shortness of breath. We compared cell lines injected either subcutaneously or intrapleurally and found that only the latter resulted in invasive and rapid growth. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Mesothelioma is a rare and universally fatal cancer linked to exposure to asbestos. Until recently, standard of care treatment was chemotherapy; a treatment resulting in a minimal survival extension, and not improved upon for almost twenty years. However, the advent of cancer immunotherapy – and in particular the immune checkpoint inhibitor class of drugs - has resulted in recently approved new treatment options, with more currently under investigation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

Continuous complete clinical remission in T-cell acute lymphoblastic leukemia (T-ALL) is now approaching 80% due to the implementation of aggressive... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• May 2010

In this review we explore the current literature about the predictive characteristics of the tumor microenvironment and discuss therapeutic approaches ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

Current approaches to staging chronic liver diseases have limited utility for predicting liver cancer risk. Here, we employed single-nucleus RNA sequencing (snRNA-seq) to characterize the cellular microenvironment of healthy and pre-malignant livers using two distinct mouse models. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Our findings provide insight into the immune cell populations important for maintaining long-term tumour dormancy in peripheral tissues ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

Sébastien Malinge SM PhD Laboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior Research Fellow (UWA), University Associate (Curtin) Sebastien.malinge@telethonkids.org.au Laboratory ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023