Limited evidence is available regarding dentists' knowledge and interpretation of infective endocarditis (IE) prophylaxis guidelines. The aim of this study was to determine understanding and management of rheumatic and non-rheumatic valvular heart disease (VHD) in the dental setting in Western Australia (WA). ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

While access to highly active antiretroviral therapy (HAART) for children with HIV has expanded and the use of HAART has substantially reduced the morbidity and mortality of children due to HIV, poor treatment outcomes among children with HIV are still a major public health problem globally. The aim of this systematic review and meta-analysis is to quantify treatment outcomes among children with HIV. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

Multidrug-resistant tuberculosis (MDR-TB) is a major global public health concern. However, there is a dearth of literature on whether MDR-TB and its medications impact maternal and perinatal outcomes, and when such evidence exists the findings are conflicting. This systematic review and meta-analysis aimed to examine the impact of MDR-TB and its medications during pregnancy on maternal and perinatal outcomes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Adolescents with polycystic ovary syndrome (PCOS) have increased incidence of cardiometabolic risk factors including dyslipidemia. Atherogenic apolipoprotein (apo) B-lipoprotein remnants are associated with increased cardiovascular disease (CVD) risk. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

This article looks at the clinical implications of the research into microbial exposure & protection against asthma. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• December 2015

Activation of receptors of the innate immune system is a critical step in the initiation of immune responses. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• February 2013

Human embryonic stem cell-derived neural stem cells (hESC-NSCs) are an attractive cell type for studying ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• April 2010

For 20 years, the hygiene hypothesis has dominated attempts to explain the increasing prevalence of allergic disease. A causal link between maternal innate immu ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• November 2010

The Bacille-Calmette–Guerin (BCG) vaccination remains the primary strategy to prevent severe disseminated TB in young children, particularly in high TB-burden countries such as Ethiopia. Accurate knowledge of vaccination coverage in small geographical areas is critically important to developing targeted immunization campaigns. Thus, this study aimed to investigate the spatiotemporal distributions and ecological level determinants of BCG vaccination coverage in Ethiopia. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

In the ongoing debate on optimum methods for identification of Indigenous people within linked administrative data, few studies have examined the impacts of method on population counts and outcomes in family-based linkage studies of Aboriginal children. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020

Rearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and re ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• October 2010

We examined the baseline profile of a panel of T-ALL cell lines to determine factors that contribute to GC resistance without prior drug selection. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2009
• June 2009