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        Real-world outcomes of insulin pump compared to injection therapy in a population-based sample of children with type 1 diabetes

        Patients using insulin pump therapy had a better long-term glycemic control relative to the matched injection therapy cohort ...

        Research

        Increased allergic immune response to Sarcoptes scabiei antigens in crusted versus ordinary scabies

        Pat Belinda Holt Hales PG BJ PhD, DSc, FRCPath, FRCPI, FAA BSc (Hons) PhD Emeritus Honorary Researcher Senior Manager, Research Platforms Patrick.Holt@telethonkids.org.au belinda.hales@telethonkids.org.au Emeritus Honorary Researcher Senior Manager ...

        Research

        An infant mouse model of influenza-driven nontypeable Haemophilus influenzae colonization and acute otitis media suitable for preclinical testing of novel therapies

        Nontypeable Haemophilus influenzae (NTHi) is a major otitis media (OM) pathogen, with colonization a prerequisite for disease development. Most acute OM is in children <5 years old, with recurrent and chronic OM impacting hearing and learning. Therapies to prevent NTHi colonization and/or disease are needed, especially for young children. Respiratory viruses are implicated in driving the development of bacterial OM in children. ...

        Research

        Inhaled corticosteroids to improve lung function in children (aged 6–12 years) who were born very preterm (PICSI): a randomised, double-blind, placebo-controlled trial

        Despite the substantial burden of lung disease throughout childhood in children who were born very preterm, there are no evidence-based interventions to improve lung health beyond the neonatal period. We tested the hypothesis that inhaled corticosteroid improves lung function in this population. ...

        Research

        Preventing perioperative respiratory complications in children with recurrent respiratory symptoms

        Elizabeth Graham Smith Hall ES GL PhD, MSc, BSc BAppSci PhD CRFS FANZSRS FThorSoc FERS Program Manager Honorary Research Associate 08 6319 1178 elizabeth.smith@telethonkids.org.au Program Manager Honorary Research Associate Dr Smith is a Respiratory ...

        Research

        How healthy (or unhealthy) is the food environment around Perth schools?

        Gina Hayley Heather Matt Trapp Christian Croll Cooper GT HC HC MC BHSc(Hons1A), RPHNutr, PhD BSc (1st Class Hons), PhD W.Aust. BHSc BCA Marketing, BSc Statistics and Applied Statistics, PhD ARC DECRA Fellow & Head of Food and Nutrition Research ...

        Research

        The impact of racial discrimination on the health of Australian Indigenous children aged 5–10 years: analysis of national longitudinal data

        Direct and persistent vicarious racial discrimination are detrimental to the physical and mental health of Indigenous children in Australia ...

        Research

        Investigating associations between birth order and autism diagnostic phenotypes

        Birth order effects have been linked to variability in intelligence, educational attainment and sexual orientation. First- and later-born children have been linked to an increased likelihood of an Autism Spectrum Disorder (ASD) diagnosis, with a smaller body of evidence implicating decreases in cognitive functioning with increased birth order. The present study investigated the potential association between birth order and ASD diagnostic phenotypes in a large and representative population sample. ...

        Research

        Amped Out: An Energy Drink Study

        Gina Matt Francis Trapp Cooper Mitrou GT MC FG BHSc(Hons1A), RPHNutr, PhD BCA Marketing, BSc Statistics and Applied Statistics, PhD BEc ARC DECRA Fellow & Head of Food and Nutrition Research Manager, Biometrics Program Head, Population Health, and ...

        Research

        Protective Vaccine Responses in Infants after Maternal Pertussis Vaccination (PRIME) Study

        Christopher Jennifer Peter Blyth Kent Richmond CC J PC MBBS (Hons) DCH FRACP FRCPA PhD RN MBBS MRCP(UK) FRACP Director, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases Epidemiology, Wesfarmers Centre of Vaccines ...

        Research

        In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma

        Ependymomas (EPN) are the third most common malignant brain cancer in children. Treatment strategies for pediatric EPN have remained unchanged over recent decades, with 10-year survival rates stagnating at just 67% for children aged 0-14 years. Moreover, a proportion of patients who survive treatment often suffer long-term neurological side effects as a result of therapy. It is evident that there is a need for safer, more effective treatments for pediatric EPN patients. ...

        Research

        Decreasing Trends in Mean HbA1c Are Not Associated With Increasing Rates of Severe Hypoglycemia in Children

        There have been concurrent improvements in HbA1c and decreasing severe hypoglycemia rates in two pediatric cohorts of type 1 diabetes ...

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