Differential network analysis of allergen-induced CD4 T cell responses can unmask covert disease-associated genes and pin point novel therapeutic targets ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

This review focuses on the scientific rationale for early intervention aimed at asthma prophylaxis and discusses therapeutic approaches ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

This paper is an editorial comment by Professor Patrick Holt on the potential for developing early intervention strategies in children with allergies and asthma ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• February 2014

We tested whether maternal vitamin D insufficiency during pregnancy is related to the autism phenotype. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

The respiratory tract is an attractive target organ for novel diagnostic and therapeutic applications with nano-sized carriers, but their immune effects and... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

The purpose of this Review was to give an overview of the recent research into whether a lack of vitamin D contributes to the development of atopy and asthma... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• June 2012

Human perinatal life is characterized by a period of extraordinary change during which newborns encounter abundant environmental stimuli and exposure to potential pathogens. To meet such challenges, the neonatal immune system is equipped with unique functional characteristics that adapt to changing conditions as development progresses across the early years of life, but the molecular characteristics of such adaptations remain poorly understood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration of immune cells into the airways. The gene networks driving the immune activation and subsequent migration of immune cells into the airways remains incompletely understood. Cellular and molecular profiling of PBMC was employed on paired samples obtained from atopic asthmatic children during acute virus-associated exacerbations and later during convalescence. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

the association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

We describe recent "omic"-level findings, and examine how these findings have been systematically integrated to generate further insight ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

The epidemic increase in the prevalence of allergic disease, which first started in the industrialized countries in the 1960s, may have reached a peak in the... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• August 2014

Eczema often precedes the development of asthma in a disease course called the 'atopic march'. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015