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        Clinical Predictors of Influenza in Young Children: The Limitations of “Influenza-Like Illness”

        This study aims to identify clinical predictors of influenza infection in children ≤5 years old from which age-specific ILI definitions are then constructed. ...

        Research

        Impact of an Ivermectin Mass Drug Administration on Scabies Prevalence in a Remote Australian Aboriginal Community.

        Scabies is endemic in many Aboriginal and Torres Strait Islander communities, with 69% of infants infected in the first year of life. ...

        Research

        Susceptibility to acute rheumatic fever based on differential expression of genes involved in cytotoxicity, chemotaxis, and apoptosis

        Differences in the immune response, detectable by gene expression, between individuals who are susceptible to ARF and those who are not ...

        Research

        World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Probiotics

        Prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10% and reaches 20-30% in those with an allergic... ...

        Research

        Invasive Staphylococcus aureus Infections in Children in Tropical Northern Australia

        We conducted a retrospective review for all cases of S aureus bacteremia and sterile site infections, for children under 15 years, in northern Australia over... ...

        Research

        Association between early bacterial carriage and otitis media in Aboriginal and non-Aboriginal children

        Streptococcus pneumoniae (Pnc), nontypeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) are the most important bacterial pathogens... ...

        Research

        A novel role for interleukin-1 receptor signaling in the developmental regulation of immune responses to endotoxin

        Suggests that IL-1R1 expression provides an additional level of Myd88-dependent signaling during this period of heighted susceptibility to infection. ...

        Research

        T-cell activation genes differentially expressed at birth in CD4+ T-cells from children who develop IgE food allergy

        To show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy. ...

        Research

        The relationship between maternal folate status in pregnancy, cord blood folate levels, and allergic outcomes in early childhood

        This study examined whether maternal and/or fetal folate status in pregnancy is associated with infant allergic outcomes. ...

        Research

        Cytokine Responses to Novel Antigens in an Indian Population Living in an Area Endemic for Visceral Leishmaniasis

        Here we employ whole blood assays to evaluate human cytokine responses to 11 of these antigens, in comparison to known defined and crude antigen preparations. ...

        Research

        Crowding and other strong predictors of upper respiratory tract carriage of otitis media-related bacteria

        Streptococcus pneumoniae, Moraxella catarrhalis, and nontypeable Haemophilus influenzae is associated with otitis media ...

        Research

        Lessons from the first year of the WAIVE study investigating the protective effect of influenza vaccine

        Influenza is major cause of paediatric hospitalisation. Influenza vaccine was offered to all children aged 6-59 months resident in Western Australia in 2008 ...

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