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        Simultaneous Targeting of DNA Replication and Homologous Recombination in Glioblastoma with a Polyether Ionophore

        Our findings highlight the potential of salinomycin to induce DNA lesions and inhibit homologous recombination to greatly enhance the effect of radiotherapy ...

        Research

        Network using Michaelis–Menten kinetics: constructing an algorithm to find target genes from expression data

        We derived a simple ordinary differential equation-based model using Michaelis–Menten Kinetics to process the microarray data ...

        Research

        Optimized peripheral blood progenitor cell mobilization for autologous hematopoietic cell transplantation in children with high-risk and refractory malignancies

        Our approach to hematopoietic progenitor cells mobilization resulted in highly effective HPC harvest in children and adolescents with high-risk cancers ...

        Research

        A method for the generation of large numbers of dendritic cells from CD34+ hematopoietic stem cells from cord blood

        Neonatal dendritic cells generated form CD34+ cord blood progenitors have a higher inflammatory potential when exposed to viral than bacterial related stimuli ...

        Research

        Early life exposure to coal mine fire smoke emissions and altered lung function in young children

        Infant exposure to coal mine fire emissions could be associated with long-term impairment of lung reactance ...

        Research

        Acute Rheumatic Fever and Rheumatic Heart Disease

        Acute Rheumatic Fever and Rheumatic Heart Disease is a concise, yet comprehensive, clinical resource highlighting must-know information on rheumatic heart disease and acute rheumatic fever from a global perspective ...

        Research

        Analytical bias in the measurement of plasma 25-hydroxyvitamin D concentrations in infants

        To our knowledge, this is the first study to show that the reported 25(OH)D concentration may be influenced by both age and assay type ...

        Research

        Topical antiseptics for chronic suppurative otitis media

        The effectiveness and safety profile of antiseptics in the treatment of chronic suppurative otitis media is uncertain ...

        Research

        Cochrane corner: interventions to prevent hearing loss caused by noise at work

        The aim of this Cochrane Review was to find out if hearing loss caused by noise at work is being prevented by current interventions ...

        Research

        The misnomer of ‘high functioning autism’: Intelligence is an imprecise predictor of functional abilities at diagnosis

        We argue that 'high functioning autism' is an inaccurate clinical descriptor when based solely on intelligence quotient demarcations ...

        Research

        Primary central nervous system lymphoma: Initial features, outcome, and late effects in 75 children and adolescents

        Children with Primary Central Nervous System Lymphoma and no immunodeficiency have a good outcome ...

        Research

        “If you don't speak from the heart, the young mob aren't going to listen at all”: An invitation for youth mental health services to engage in new ways of working

        Building Bridges demonstrates the centrality of trusting relationships for systemic change and the way in which meaningful engagement is at the core of both the process and the outcome ...

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