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        Early childhood education quality and child development in Lao PDR

        Globally, as scale up of early childhood education (ECE) continues, monitoring ECE quality is imperative to promote service aspects that drive positive outcomes for children. Monitoring of ECE quality in low- and middle-income countries (LMICs) is scarce, limited by challenges in varied conceptualisations of quality, lack of measurement tools that reflect local culture and context, and implementation difficulties in low resource settings. ...

        Research

        FDA-approved disulfiram as a novel treatment for aggressive leukemia

        Acute leukemia continues to be a major cause of death from disease worldwide and current chemotherapeutic agents are associated with significant morbidity in survivors. While better and safer treatments for acute leukemia are urgently needed, standard drug development pipelines are lengthy and drug repurposing therefore provides a promising approach. ...

        Research

        Early introduction of food reduces food allergy – Pro and Con

        When an infant is developmentally ready, a variety of nutritious foods should be introduced including the ‘more allergenic’ foods during infancy ...

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        Older maternal age is associated with depression, anxiety, and stress symptoms in young adult female offspring

        Older maternal age is associated with depression, anxiety, and stress symptoms in young adult females ...

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        Characterization of regulatory dendritic cells differentiated from the bone marrow of UV-irradiated mice

        In summary, UV-BMDCs do not express the classical phenotypic or gene expression properties of DCs reported by others as 'regulatory' or 'tolerogenic'. ...

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        Androgen concentrations in umbilical cord blood and their association with maternal, fetal and obstetric factors

        The aim of this study was to measure umbilical blood androgen concentrations in a birth cohort using a highly specific liquid chromatography-tandem mass... ...

        Research

        Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhood

        Preliminary evidence suggests that prenatal testosterone exposure may be associated with language delay. ...

        Research

        Idiosyncratic nature of voriconazole photosensitivity in children undergoing cancer therapy

        In adults, the unpredictability of voriconazole pharmacokinetics, particularly in those patients receiving chemotherapy, is well recognised. A paucity of... ...

        Research

        Intellectual disability and other neuropsychiatric outcomes in high-risk children of mothers with schizophrenia, bipolar disorder and unipolar major depression

        We examined risk of intellectual disability and other neuropsychiatric outcomes in children of mothers with and without schizophrenia, bipolar or depression. ...

        Research

        Premature to conclude no genetic basis to the association between smoking and major depressive disorder

        We analyzed two large-scale surveys, and found high rates of smoking in people with mood disorders and both with and without substance dependence disorders. ...

        Research

        Change in Gross Motor Abilities of Girls and Women With Rett Syndrome Over a 3- to 4-Year Period

        We describe change in gross motor function over 3 to 4 years for 70 subjects participating in the Australian Rett Syndrome Database ...

        Research

        Evidence for associations between the purinergic receptor P2X(7) (P2RX7) and toxoplasmosis

        Congenital Toxoplasma gondii infection can result in intracranial calcification, hydrocephalus and retinochoroiditis. Acquired infection is commonly associated ...

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