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        Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia

        The aim of our study was to investigate whether CBL0137 has potential as a therapeutic and chemopotentiating compound in MLL-r leukemia ...

        Research

        Serotonin and aggressive behaviour in children and adolescents: a systematic review

        Findings were mixed, with support both for negative and for positive associations of central nervous 5-HT function with aggression in children and adolescents ...

        Research

        Viral Induced Effects on a Vulnerable Epithelium; Lessons Learned From Paediatric Asthma and Eosinophilic Oesophagitis

        The epithelium is integral to the protection of many different biological systems and for the maintenance of biochemical homeostasis. Emerging evidence suggests that particular children have epithelial vulnerabilities leading to dysregulated barrier function and integrity, that resultantly contributes to disease pathogenesis. ...

        Research

        Bias in student survey findings from active parental consent procedures

        This study assessed the potential bias present in a sample of actively consented students, and in the estimates of associations between variables obtained... ...

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        Sustained participation in annual continuous quality improvement activities improves quality of care for Aboriginal and Torres Strait Islander children

        To determine whether participation in the CQI Audit and Best Practice for Chronic Disease programme improved care and outcomes for Indigenous children. ...

        Research

        Status of research and development of vaccines for Streptococcus pyogenes

        Vaccines against Streptococcus pyogenes are considered as impeded vaccines because of a number of crucial barriers to development ...

        Research

        Developing a Model to Account for Attrition Bias in a Longitudinal Cohort

        Our objective was to develop a method that could be applied in a longitudinal cohort study to account for attrition bias in an investigation of exclusive... ...

        Research

        Optimized 25-hydroxyvitamin D analysis using liquid-liquid extraction with 2D separation with LC/MS/MS detection, provides superior precision

        The analysis of 25-hydroxyvitamin D3 (25(OH)D3) and related metabolites represents a considerable challenge for both clinical and research laboratories... ...

        Research

        Lifestyle and demographic correlates of poor mental health in early adolescence

        To determine the constellation of lifestyle and demographic factors that are associated with poor mental health in an adolescent population. ...

        Research

        Level of purposeful hand function as a marker of clinical severity in Rett syndrome

        Helen Peter Leonard Jacoby HM PJ MBChB MPH BA (Hons) MSc Principal Research Fellow Biostatistician +61 419 956 946 helen.leonard@telethonkids.org.au Peter.Jacoby@telethonkids.org.au Principal Research Fellow Biostatistician Authors: Downs J, ...

        Research

        Onset of maternal psychiatric disorders after the birth of a child with intellectual disability: A retrospective cohort study

        Mothers of a child with intellectual disability (ID) have more psychiatric disorders after the birth of their child than other mothers. ...

        Research

        Influence of the environment on participation in social roles for young adults with down syndrome

        The purpose of this study is to describe the social participation of young adults with Down syndrome and examine its relationship with the physical and... ...

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