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        Structural determinants of long term functional outcomes in young children with cystic fibrosis

        Chest CT identifies children at an early age who have adverse long-term outcomes ...

        Research

        Maternal alcohol use disorder and subsequent child protection contact: A record-linkage population cohort study

        We examined the relationship between a maternal alcohol-use diagnosis, and the timing of diagnosis, and child protection outcomes in a WA population cohort. ...

        Research

        Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it?

        This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research ...

        Research

        The impact of racial discrimination on the health of Australian Indigenous children aged 5–10 years: analysis of national longitudinal data

        Direct and persistent vicarious racial discrimination are detrimental to the physical and mental health of Indigenous children in Australia ...

        Research

        Global supermarkets' corporate social responsibility commitments to public health: A content analysis

        Investigate the world's largest and most powerful supermarkets' publically available CSR commitments to determine their potential impact on public health ...

        Research

        Prenatal maternal stress events and phenotypic outcomes in Autism Spectrum Disorder

        ASD, in the context of prenatal maternal stress exposure, may be associated with a more severe phenotype, particularly when there are multiple prenatal exposures ...

        Research

        Elastase Exocytosis by Airway Neutrophils Associates with Early Lung Damage in Cystic Fibrosis Children

        Protease elastase exocytosis by airway neutrophils occurs in all cystic fibrosis children, and its cellular measure correlates with early lung damage ...

        Research

        Trial refresh: A case for an adaptive platform trial for pulmonary exacerbations of cystic fibrosis

        This review will discuss the necessary steps required for a Bayesian adaptive platform trial to optimize treatment of pulmonary exacerbations of cystic fibrosis ...

        Research

        Discrete choice experiment to evaluate preferences of patients with cystic fibrosis among alternative treatment-related health outcomes: A protocol

        The aim of this study is to identify and quantify the preferences of patients with cystic fibrosis regarding treatment outcomes ...

        Research

        Increasing incidence of invasive group A streptococcal disease in Western Australia, particularly among Indigenous people

        The incidence of invasive GAS disease in WA increased between 2000 and 2018, particularly among Indigenous Australians. Mandatory notification of invasive GAS disease would therefore be appropriate. The social determinants of differences in incidence should be addressed, and other relevant host, pathogen, and health system factors investigated. ...

        Research

        Targeting host-microbial interactions to develop otitis media therapies

        Otitis media (OM; middle ear infection) is the most common reason for pre-school children to visit a doctor, be prescribed antimicrobials, or undergo surgery. Recent Cochrane reviews of clinical trials have identified that antibiotics and grommet surgery are only moderately effective in treating OM, with recurrent or persistent infection observed in one-third of children. Research efforts are focusing on developing improved therapies to treat OM and prevent disease recurrence. ...

        Research

        Official ERS technical standard: Global Lung Function Initiative reference values for static lung volumes in individuals of European ancestry

        Measurement of lung volumes across the life course is critical to the diagnosis and management of lung disease. The aim of the study was to use the Global Lung Function Initiative methodology to develop all-age multi-ethnic reference equations for lung volume indices determined using body plethysmography and gas dilution techniques. ...

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