Esophageal cancer is a highly aggressive malignancy with a low response to standard anti-cancer therapies. There is an unmet need to develop new therapeutic strategies to improve the clinical outcomes of current treatments. Cold atmospheric plasma (CAP) is a promising approach for cancer treatment, and has displayed anticancer efficacy in multiple preclinical models. Recent studies have shown that the efficacy of CAP is positively correlated with intracellular reactive oxygen species (ROS) levels. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

We conclude that genuine serious allergic reaction to propofol is rare and is not reliably predicted by a history of food allergy ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• October 2019

Gina Joelie Trapp Mandzufas GT JM BHSc(Hons1A), RPHNutr, PhD BCom BHSc GCHELT ARC DECRA Fellow & Head of Food and Nutrition Research Project Coordinator 0410 589 374 Gina.Trapp@telethonkids.org.au Joelie.mandzufas@telethonkids.org.au ARC DECRA ...

• 1. Telethon Kids Institute
• Projects

Alexander David Deborah Larcombe Martino Strickland A DM DH BScEnv (Hons) PhD BSc PhD PhD Team Leader, Respiratory Environmental Health Head, Clinical Epigenetics Program Head, Immunobiology and Immunotherapeutic Program David.Martino@ ...

• 1. Telethon Kids Institute
• Projects

Antenatal inactivated influenza and pertussis-containing vaccines offer protection against severe respiratory infections for pregnant women and infants <6 months of age. Both vaccines are recommended in pregnancy; however, little is known about temporal or jurisdictional trends and predictors of uptake. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

Respiratory syncytial virus (RSV) reinfection in children is poorly understood. We examined the incidence, characteristics, and outcomes of hospital-attended RSV reinfections in children <16 years in Western Australia between 2012 and 2022. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

Psychological distress in the early postpartum period can have long-lasting deleterious effects on a mother's well-being and negatively affect her infant's development. Intervention approaches based in contemplative practices such as mindfulness and loving-kindness and compassion are intended to alleviate distress and cultivate well-being and can be delivered effectively as digital mental health interventions. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

The potential for human-computer interaction to have a substantial impact on adults is well documented. However, its potential importance prior to birth has rarely been reported. Parental use of smartphones and tablet computers could influence the relationship between parent and baby during pregnancy (prenatal attachment) and thus child development. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

Parainfluenza viruses are significant contributors to childhood respiratory illness worldwide, although detailed epidemiological studies are lacking. Few recent Australian studies have investigated serotype-specific PIV epidemiology, and there is a paucity of southern hemisphere PIV reports. We report age-stratified PIV hospitalisation rates and a mathematical model of PIV seasonality and dynamics in Western Australia (WA). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

People living in new developments, and low SES areas of Perth, may be disadvantaged with poorer access to healthy food and greater exposure to unhealthy food outlets ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019

The provision of shade, particularly through natural forms such as tree canopy, is an important sun protection strategy and enabler of outdoor time ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

To understand how HLA-DR contributes to disease pathogenesis, we examined expression at the protein level in circulating myeloid and lymphoid cells of VL patients ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• February 2019