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        121-132 of 1480 results for 'Infectious disease'

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        The role of chronic infection in children with otitis media with effusion: Evidence for intracellular persistence of bacteria

        Demonstrate mucosal bacterial infection in children with otitis media with effusion (OME). ...

        Research

        Bacterial and Fungal Gut Community Dynamics Over the First 5 Years of Life in Predominantly Rural Communities in Ghana

        Bacterial and fungal microbiotas are increasingly recognized as important in health and disease starting early in life. However, microbiota composition has not yet been investigated in most rural, low-resource settings, and in such settings, bacterial and fungal microbiotas have not been compared. ...

        Research

        An observational study of antibody responses to a primary or subsequent pertussis booster vaccination in Australian healthcare workers

        Adult pertussis vaccination is increasingly recommended to control pertussis in the community. However, there is little data on the duration and kinetics of immunity to pertussis boosters in adults. We compared IgG responses to vaccination with a tetanus, low-dose diphtheria, low-dose acellular pertussis (Tdap) booster at 1 week, 1 month and 1 year post-vaccination in whole-cell (wP)-primed Australian paediatric healthcare workers who had received an adult Tdap booster 5-12 years previously, to those who received their first Tdap booster. Tdap vaccination was well tolerated in both groups. ...

        Research

        An observational study of antibody responses to a primary or subsequent pertussis booster vaccination in Australian healthcare workers

        Adult pertussis vaccination is increasingly recommended to control pertussis in the community. However, there is little data on the duration and kinetics of immunity to pertussis boosters in adults. We compared IgG responses to vaccination with a tetanus, low-dose diphtheria, low-dose acellular pertussis (Tdap) booster at 1 week, 1 month and 1 year post-vaccination in whole-cell (wP)-primed Australian paediatric healthcare workers who had received an adult Tdap booster 5-12 years previously, to those who received their first Tdap booster. ...

        Research

        CASSETTE: Clindamycin Adjunctive therapy for Severe Staphylococcus aurEus Treatment Evaluation, a multi-centre, pilot randomised controlled trial

        Asha Tom Bowen Snelling AC T BA MBBS DCH FRACP PhD GAICD BMBS DTMH GDipClinEpid PhD FRACP Team Lead, Healthy Skin and ARF Prevention Head, Infectious Disease Implementation Research 08 6319 1817 tom.snelling@telethonkids.org.au Team Lead, Healthy ...

        Research

        Excess respiratory mortality and hospitalizations associated with influenza in Australia, 2007-2015

        Influenza is the most common vaccine-preventable disease in Australia, causing significant morbidity and mortality. We assessed the burden of influenza across all ages in terms of influenza-associated mortality and hospitalizations using national mortality, hospital-discharge and influenza surveillance data. ...

        Research

        Variants of Streptococcus pneumoniae Serotype 14 from Papua New Guinea with the Potential to Be Mistyped and Escape Vaccine-Induced Protection

        Streptococcus pneumoniae (the pneumococcus) is a human pathogen of global importance, classified into serotypes based on the type of capsular polysaccharide produced. Serotyping of pneumococci is essential for disease surveillance and vaccine impact measurement. ...

        Research

        COVID-19 vaccine knowledge, attitudes, and experiences of health care workers in Perth, Western Australia: A qualitative study

        Health care workers (HCWs) faced an increased risk of Coronavirus Disease 2019 (COVID-19). Australia’s COVID-19 vaccine rollout commenced in February 2021 to priority groups, including HCWs. Given their increased risk, as well as influence on patients’ vaccine uptake, it was important that HCWs had a positive COVID-19 vaccination experience, as well as trusting the vaccine safety and efficacy data. ...

        Research

        Microbiological and immunological factors predicting surgical outcomes for chronic otitis media

        Lea-Ann Peter Ruth Kirkham Richmond Thornton LK PC RT PhD MBBS MRCP(UK) FRACP PhD Co-Head, Bacterial Respiratory Infectious Disease Group; Microbiology Lead, Wesfarmers Centre of Vaccines & Infectious Diseases Head, Vaccine Trials Group Co-head, ...

        Research

        Statistical modeling based on structured surveys of Australian native possum excreta harboring Mycobacterium ulcerans predicts Buruli ulcer occurrence in humans

        Buruli ulcer (BU) is a neglected tropical disease caused by infection of subcutaneous tissue with Mycobacterium ulcerans. BU is commonly reported across rural regions of Central and West Africa but has been increasing dramatically in temperate southeast Australia around the major metropolitan city of Melbourne, with most disease transmission occurring in the summer months. ...

        Research

        Pathogenesis of obstructive sleep apnoea

        Lea-Ann Peter Ruth Kirkham Richmond Thornton LK PC RT PhD MBBS MRCP(UK) FRACP PhD Co-Head, Bacterial Respiratory Infectious Disease Group; Microbiology Lead, Wesfarmers Centre of Vaccines & Infectious Diseases Head, Vaccine Trials Group Co-head, ...

        Research

        Consensus guidelines for improving patients' understanding of invasive fungal disease and related risk prevention in the haematology/oncology setting, 2021

        Patients with invasive fungal disease (IFD) are at significant risk of morbidity and mortality. A productive partnership between patients, their carers/families, and the multidisciplinary team managing the infection and any underlying conditions, is essential. ...

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