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        121-132 of 184 results for 'malaria'

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        COVID-19 vaccine coverage targets to inform reopening plans in a low incidence setting

        Since the emergence of SARS-CoV-2 in 2019 through to mid-2021, much of the Australian population lived in a COVID-19-free environment. This followed the broadly successful implementation of a strong suppression strategy, including international border closures. With the availability of COVID-19 vaccines in early 2021, the national government sought to transition from a state of minimal incidence and strong suppression activities to one of high vaccine coverage and reduced restrictions but with still-manageable transmission. ...

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        A modelling approach to estimate the transmissibility of SARS-CoV 2 during periods of high, low, and zero case incidence

        Against a backdrop ofwidespread global transmission, a number of countries have successfully brought large outbreaks of COVID-19 under control and maintained near-elimination status. A key element of epidemic response is the tracking of disease transmissibility in near real-time. During major out-breaks, the effective reproduction number can be estimated froma time-series of case, hospitalisation or death counts. In low or zero incidence settings, knowing the potential for the virus to spread is a response priority. ...

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        Association between mental health workforce supply and clusters of high and low rates of youth suicide: An Australian study using suicide mortality data from 2016 to 2020

        Abstract: To examine the association between mental health workforce supply and spatial clusters of high versus low incidence of youth suicide. ...

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        Geospatial analysis of Japanese Encephalitis virus (JEV) transmission risk

        Nick Freya David Golding Shearer Duncan NG FS DD BSc DPhil BSc DPhil BSc PhD Honorary Research Fellow Honorary Research Associate Senior Infectious Disease Modeller Nick.Golding@telethonkids.org.au david.duncan@telethonkids.org.au Honorary Research ...

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        Estimating the impact of test–trace–isolate–quarantine systems on SARS-CoV-2 transmission in Australia

        Australian states and territories used test-trace-isolate-quarantine (TTIQ) systems extensively in their response to the COVID-19 pandemic in 2020-2021. We report on an analysis of Australian case data to estimate the impact of test-trace-isolate-quarantine systems on SARS-CoV-2 transmission.  ...

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        Could late-latent syphilis be treated with a single subcutaneous infusion of long-acting penicillin?

        Syphilis is an important global health threat and little has changed in its treatment since the mid-20th century. For late-latent or syphilis infection of unknown duration, the standard treatment of multiple intramuscular injections of benzathine penicillin G (BPG) are associated with significant pain and distress to clients and caregivers, negatively impacting on treatment completion. ...

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        Serological Responses to Streptococcus pyogenes Vaccine Candidate Antigens Suggests That Streptococcus dysgalactiae Is the Predominant Cause of Lower Limb Cellulitis

        A future Streptococcus pyogenes (Strep A) vaccine will ideally prevent a significant burden of lower limb cellulitis; however, natural immune responses to proposed vaccine antigens following an episode of cellulitis remain uncharacterized. ...

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        Patient preferences for prophylactic regimens requiring regular injections in children and adolescents: A systematic review and thematic analysis

        At present, limited literature exists exploring patient preferences for prophylactic treatment of acute rheumatic fever and rheumatic heart disease. Given low treatment completion rates to this treatment in Australia, where the burden of disease predominantly affects Aboriginal and Torres Strait Islander people, an improved understanding of factors driving patient preference is required to improve outcomes. ...

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        Introduction of Aedes aegypti mosquitoes carrying wAlbB Wolbachia sharply decreases dengue incidence in disease hotspots

        Partial replacement of resident Aedes aegypti mosquitoes with introduced mosquitoes carrying certain strains of inherited Wolbachia symbionts can result in transmission blocking of dengue and other viruses of public health importance. Wolbachia strain wAlbB is an effective transmission blocker and stable at high temperatures, making it particularly suitable for hot tropical climates. ...

        Research

        Reach and perceived effectiveness of a community-led active outreach postvention intervention for people bereaved by suicide

        Postvention is a core component of suicide prevention strategies, internationally. However, the types of supports provided to people impacted by suicide vary widely. This study examines the perceived effectiveness of the Primary Care Navigator (PCN) model for people bereaved by suicide. The PCN model was implemented in response to a suicide cluster. ...

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        Modelling to support Australia's COVID-19 response

        Nick Nicholas Sherlynn Golding Tierney Ang NG NT SA BSc DPhil B.Psych.Sci (Hons), PhD (Statistics) BSc(Hons) Honorary Research Fellow Research Software Engineer Project Manager Nick.Golding@telethonkids.org.au nicholas.tierney@telethonkids.org.au ...

        Research

        Immunogenetics of Parasitic and Bacterial Disease

        Here we focus on more recent well-powered genome-wide association studies, including malaria, leprosy, tuberculosis, and visceral leishmaniasis ...

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