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        Primary Nasal Epithelial Cells as a Surrogate Cell Culture Model for Type-II Alveolar Cells to Study ABCA-3 Deficiency

        ATP Binding Cassette Subfamily A Member 3 (ABCA-3) is a lipid transporter protein highly expressed in type-II alveolar (AT-II) cells. Mutations in ABCA3 can result in severe respiratory disease in infants and children. To study ABCA-3 deficiency in vitro, primary AT-II cells would be the cell culture of choice although sample accessibility is limited. Our aim was to investigate the suitability of primary nasal epithelial cells, as a surrogate culture model for AT-II cells, to study ABCA-3 deficiency. ...

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        Phage therapy for multi-drug resistant respiratory tract infections

        The emergence of multi-drug resistant (MDR) bacteria is recognised today as one of the greatest challenges to public health. As traditional antimicrobials are becoming ineffective and research into new antibiotics is diminishing, a number of alternative treatments for MDR bacteria have been receiving greater attention. Bacteriophage therapies are being revisited and present a promising opportunity to reduce the burden of bacterial infection in this post-antibiotic era. ...

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        The relationship between physical activity, self-regulation and cognitive school readiness in preschool children

        Limited research exists on the pathways through which physical activity influences cognitive development in the early years. This study examined the direct and indirect relationships between physical activity, self-regulation, and cognitive school readiness in preschool children. ...

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        BEAT-CF: Bayesian Evidence-Adaptive Tool to optimise management of Cystic Fibrosis

        Stephen André Stick Schultz SM AS MB BChir PhD MRCP FRACP MBChB, PhD, FRACP Head, P4 Respiratory Health for Kids Program Head, Respiratory Health RFA Head, P4 Respiratory Health for Kids Program Head, Respiratory Health RFA Areas for research ...

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        DEFEND CF: Biomarkers to define the treatment end-point for pulmonary exacerbations in cystic fibrosis

        Stephen Graham Stick Hall SM GL MB BChir PhD MRCP FRACP BAppSci PhD CRFS FANZSRS FThorSoc FERS Head, P4 Respiratory Health for Kids Honorary Research Associate Head, P4 Respiratory Health for Kids Honorary Research Associate Areas for research ...

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        Defining the cellular immune response to vaccines for enhanced protection from invasive pneumococcal disease

        Peter Lea-Ann Ruth Richmond Kirkham Thornton PC LK RT MBBS MRCP(UK) FRACP PhD PhD Head, Vaccine Trials Group Co-Head, Bacterial Respiratory Infectious Disease Group; Microbiology Lead, Wesfarmers Centre of Vaccines & Infectious Diseases Co-head, ...

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        Developing a novel therapeutic pipeline for antibiotic resistant bacterial lung infection in children: investigating and assessing the potential phage therapy

        Anthony Stephanie Stephen Kicic Trend Stick A ST SM BSc (Hons) PhD BSc PhD MB BChir PhD MRCP FRACP Rothwell Family Fellow; Head, Airway Epithelial Research Honorary Research Associate Head, P4 Respiratory Health for Kids 6319 1430 Anthony.Kicic@ ...

        Research

        Maximising fathers’ roles in preventing adolescent alcohol-related harm. (Fathers and Adolescent Alcohol Use Project)

        Robyn Karen Gina Karen Johnston Lombardi Trapp Forde RJ KL GT KF BSc, Post Grad Dip, PhD BHSc (Hons), PhD BHSc(Hons1A), RPHNutr, PhD BHlthSc (Hons 1A) Senior Research Officer Research Fellow ARC DECRA Fellow & Head of Food and Nutrition Research ...

        Research

        Pathogenesis of obstructive sleep apnoea

        Lea-Ann Peter Ruth Kirkham Richmond Thornton LK PC RT PhD MBBS MRCP(UK) FRACP PhD Co-Head, Bacterial Respiratory Infectious Disease Group; Microbiology Lead, Wesfarmers Centre of Vaccines & Infectious Diseases Head, Vaccine Trials Group Co-head, ...

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        A randomised-controlled trial of a behavioural intervention for optimising social and communication development in newborns at increased likelihood of autism spectrum disorders

        Andrew Kandice Matt Melissa Whitehouse Watch and listen to Andrew Varcin Cooper Licari AJ KJ MC ML PhD M.Psych (Clinical), PhD BCA Marketing, BSc Statistics and Applied Statistics, PhD PhD Angela Wright Bennett Professor of Autism Research at ...

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        An investigation of parental mental health among the Aboriginal population in Western Australia, and its impact on children’s outcomes

        Carrington Fiona Shepherd Stanley CCJ FJ PhD FAA FASSA MSc MD FFPHM FAFPHM FRACP FRANZCOG HonDSc HonDUniv HonFRACGP HonMD HonFRCPCH HonLLB (honoris causa) Honorary Research Associate Patron 08 6319 1176 contact@telethonkids.org.au Honorary Research ...

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        Early life influences on cardio-metabolic disease risk in aboriginal populations-what is the evidence? A systematic review

        We systematically reviewed the published evidence for the developmental origins of health and disease hypothesis among aboriginal populations from Australia,... ...

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