Severe, invasive Streptococcus pyogenes (Strep A) infections result in greater than 500,000 deaths annually. First line treatment for such infections is benzylpenicillin, often with the addition of clindamycin, but treatment failure can occur with this regimen. This failure has been partially attributed to the inoculum effect, which presents as reduced antibiotic susceptibility during high bacterial density and plateau-phase growth. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

Scabies, impetigo, and other skin and soft tissue infections (SSTIs) are highly prevalent in many tropical, low-middle income settings, but information regarding their burden of disease is scarce. We conducted surveillance of presentations of scabies and SSTIs, including impetigo, abscesses, cellulitis, and se≈vere SSTI, to primary health facilities in Fiji. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

We describe the birth prevalence and characteristics of congenital heart defects in a geographically defined Australian population. This descriptive, population-based study examined congenital heart defects in live births, stillbirths and pregnancy terminations ascertained by the Western Australian Register of Developmental Anomalies, 1990-2016. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

Our data set provides a useful reference point for genomic studies on Aboriginal Australians ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

We argue that 'high functioning autism' is an inaccurate clinical descriptor when based solely on intelligence quotient demarcations ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

To our knowledge, this is the first study to show that the reported 25(OH)D concentration may be influenced by both age and assay type ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

The effectiveness and safety profile of antiseptics in the treatment of chronic suppurative otitis media is uncertain ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

Neonatal dendritic cells generated form CD34+ cord blood progenitors have a higher inflammatory potential when exposed to viral than bacterial related stimuli ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

Infant exposure to coal mine fire emissions could be associated with long-term impairment of lung reactance ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

Our approach to hematopoietic progenitor cells mobilization resulted in highly effective HPC harvest in children and adolescents with high-risk cancers ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

Acute Rheumatic Fever and Rheumatic Heart Disease is a concise, yet comprehensive, clinical resource highlighting must-know information on rheumatic heart disease and acute rheumatic fever from a global perspective ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

The aim of this Cochrane Review was to find out if hearing loss caused by noise at work is being prevented by current interventions ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020