Good language development is an integral component of school readiness and academic achievement. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

We employed a systems biology approach to delineate upper airway gene network patterns underlying asthma exacerbation phenotypes in children. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

The global burden of non-communicable diseases (NCDs) continues to grow. Although developing settings face fastest growth in incidence, no country is exempt. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015

Glioblastoma is the most common form of high-grade glioma in adults and has a poor survival rate with very limited treatment options. There have been no significant advancements in glioblastoma treatment in over 30 years. Epidermal growth factor receptor is upregulated in most glioblastoma tumours and, therefore, has been a drug target in recent targeted therapy clinical trials. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

Normal in utero lung development and growth rely upon the expansion of airspaces and the controlled efflux of lung liquid into the amniotic space. Infants with congenital diaphragmatic hernia (CDH) also have lung hypoplasia due to occupation of the chest cavity by the stomach and bowel and, in the most severe cases, the liver. Balloon tracheal occlusion reduces the severity of lung hypoplasia in fetuses with CDH but increases the risk of premature birth. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

The broadening of the clinical definition of autism over time-the so-called, autism spectrum-has run in parallel with the growth of a neurodiversity movement that has reframed the concept of autism entirely. Without a coherent and evidence-based framework through which both of these advances can be situated, the field is at risk of losing definition altogether. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

Adverse pregnancy outcomes including maternal mortality, stillbirth, preterm birth, intrauterine growth restriction cause millions of deaths each year. More effective interventions are urgently needed. Maternal immunization could be one such intervention protecting the mother and newborn from infection through its pathogen-specific effects. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

This study investigated whether a prior bout of moderate-intensity exercise attenuates the glycemia-increasing effect of a maximal 30-sec sprint. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• February 2015

We recently identified C. pseudodiphtheriticum and D. pigrum as the major nasopharyngeal species associated with resistance to recurrent ear infections ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

We find that DNA methylation in neonatal blood is associated with birthweight, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

In this review, we discuss the different subsets of tumor-infiltrating dendritic cells and their role in anti-tumor immunity ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at the Telethon Institute in 2005 and is now a Senior Research ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021