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        133-144 of 666 results for 'early lung health'

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        What doctors should consider before prescribing e-liquids for e-cigarettes

        Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at the Telethon Institute in 2005 and is now a Senior Research ...

        Research

        COMBAT CF: A phase 3 multi-centre randomized placebo-controlled study of azithromycin in the primary prevention of radiologically-defined bronchiectasis in infants with cystic fibrosis.

        Stephen Stick SM MB BChir PhD MRCP FRACP Head, P4 Respiratory Health for Kids Head, P4 Respiratory Health for Kids Areas for research expertise: Research Interests; Paediatric respiratory disease; Cystic fibrosis; Respiratory epithelium; Lung ...

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        Increasing airway obstruction through life following bronchopulmonary dysplasia: a meta-analysis

        Few studies exist investigating lung function trajectories of those born preterm; however growing evidence suggests some individuals experience increasing airway obstruction throughout life. Here we use the studies identified in a recent systematic review to provide the first meta-analysis investigating the impact of preterm birth on airway obstruction measured by the forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) ratio. ...

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        Cystic Fibrosis Early Surveillance Program

        Stephen Yuliya Stick Karpievitch SM YK MB BChir PhD MRCP FRACP PhD, MS, BS Head, P4 Respiratory Health for Kids Ai and Data Analytics Lead, Respiratory Research +61863191356 yuliya.karpievitch@telethonkids.org.au Head, P4 Respiratory Health for Kids ...

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        Of pigs, mice, and men: Understanding early triggers of cystic fibrosis lung disease

        Understanding early triggers of Cystic Fibrosis Lung Disease ...

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        Bacteriophage: A new therapeutic player to combat neutrophilic inflammation in chronic airway diseases

        Persistent respiratory bacterial infections are a clinical burden in several chronic inflammatory airway diseases and are often associated with neutrophil infiltration into the lungs. Following recruitment, dysregulated neutrophil effector functions such as increased granule release and formation of neutrophil extracellular traps (NETs) result in damage to airway tissue, contributing to the progression of lung disease. ...

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        Dissecting the regulation of bile-induced biofilm formation in staphylococcus aureus

        Wall teichoic acid may be important for protecting S. aureus against exposure to bile ...

        Research

        Standardised treatment and monitoring protocol to assess safety and tolerability of bacteriophage therapy for adult and paediatric patients (STAMP study): protocol for an open-label, single-arm trial

        There has been renewed interest in the therapeutic use of bacteriophages (phages); however, standardised therapeutic protocols are lacking, and there is a paucity of rigorous clinical trial data assessing efficacy. ...

        Research

        Association between diesel engine exhaust exposure and lung function in Australian gold miners

        Diesel engine exhaust exposures were higher in underground miners and had a negative association with their lung function over a single 12-h shift ...

        Research

        Acute diesel exhaust particle exposure increases viral titre and inflammation associated with existing influenza

        Exposure to diesel exhaust particles (DEP) is thought to exacerbate many pre-existing respiratory diseases. ...

        Research

        Factors influencing the assessment of lung function in mice with influenza-induced lung disease

        The constant-phase model (CPM) is commonly fit to respiratory system input impedance (Z rs) to estimate lung mechanics. ...

        Research

        Primary Nasal Epithelial Cells as a Surrogate Cell Culture Model for Type-II Alveolar Cells to Study ABCA-3 Deficiency

        ATP Binding Cassette Subfamily A Member 3 (ABCA-3) is a lipid transporter protein highly expressed in type-II alveolar (AT-II) cells. Mutations in ABCA3 can result in severe respiratory disease in infants and children. To study ABCA-3 deficiency in vitro, primary AT-II cells would be the cell culture of choice although sample accessibility is limited. Our aim was to investigate the suitability of primary nasal epithelial cells, as a surrogate culture model for AT-II cells, to study ABCA-3 deficiency. ...

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