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        133-144 of 344 results for 'early years system'

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        Improved Survival in Down Syndrome over the Last 60 Years and the Impact of Perinatal Factors in Recent Decades

        Improved survival for children born with Down syndrome over the last 60 years has occurred incrementally, but disparities still exist ...

        Research

        Preterm birth and exercise capacity: what do we currently know?

        The long-term cardiopulmonary outcomes following preterm birth during the surfactant era remain unclear. Respiratory symptoms, particularly exertional symptoms, are common in preterm children. Therefore, cardiopulmonary exercise testing may provide insights into the pathophysiology driving exertional respiratory symptoms in those born preterm. This review aims to outline the current knowledge of cardiopulmonary exercise testing in the assessment of children born preterm in the surfactant era. ...

        Research

        Developmental regulation of type 1 and type 3 interferon production and risk for infant infections and asthma development

        Type 1 and 3 interferon response capacity appears strongly developmentally constrained at birth ...

        Research

        Evaluation of the implementation and clinical effects of an intervention to improve medical follow-up and health outcomes for Aboriginal children hospitalised with chest infections

        Aboriginal children hospitalised with acute lower respiratory infections (ALRIs) are at-risk of developing bronchiectasis, which can progress from untreated protracted bacterial bronchitis, often evidenced by a chronic (>4 weeks) wet cough following discharge. We aimed to facilitate follow-up for Aboriginal children hospitalised with ALRIs to provide optimal management and improve their respiratory health outcomes. ...

        Research

        LPS binding protein and activation signatures are upregulated during asthma exacerbations in children

        Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration of immune cells into the airways. The gene networks driving the immune activation and subsequent migration of immune cells into the airways remains incompletely understood. Cellular and molecular profiling of PBMC was employed on paired samples obtained from atopic asthmatic children during acute virus-associated exacerbations and later during convalescence. ...

        Research

        Gestational age and child development at school entry

        Studies have reported a dose-dependent relationship between gestational age and poorer school readiness. The study objective was to quantify the risk of developmental vulnerability for children at school entry, associated with gestational age at birth and to understand the impact of sociodemographic and other modifiable risk factors on these relationships. Linkage of population-level birth registration, hospital, and perinatal datasets to the Australian Early Development Census (AEDC), enabled follow-up of a cohort of 64,810 singleton children, from birth to school entry in either 2009, 2012, or 2015. ...

        Research

        Respiratory impedance and bronchodilator responsiveness in healthy children aged 2-13 years

        There is limited information on changes in FOT outcomes in healthy children beyond the preschool years and the level of bronchodilator responsiveness (BDR)... ...

        Research

        Water Quality and the Microbiome Study (TUMS): The effects of chlorinated drinking water on the assembly of the infant gut microbiome

        David Debbie Desiree Matt Susan Martino Palmer Silva Cooper Prescott DM D DS MC SL BSc PhD BSc BND PhD MBBS, FRACP, MPH, PhD BCA Marketing, BSc Statistics and Applied Statistics, PhD MBBS BMedSci PhD FRACP Head, Clinical Epigenetics Head, Early Life ...

        Research

        A randomised controlled trial of an iPad-based application to complement early behavioural intervention in Autism Spectrum Disorder

        Technology-based interventions may provide a relatively low-cost addition to existing therapist-delivered interventions for children with ASD ...

        Research

        Raising strong, solid Koolunga: Values and beliefs about early child development among Perth's Aboriginal community

        We detail the unique findings from an Aboriginal early child development research project with a specific focus on the Nyoongar/Aboriginal community of Perth ...

        Research

        A marked shift in innate and adaptive immune response in chinese immigrants living in a western environment

        There is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years ...

        Research

        Prevalence of Racial Discrimination in a Cohort of Aboriginal and Torres Strait Islander Children

        This study looked at the frequency of racism experiences over time in a population of Aboriginal and Torres Strait Islander children ...

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