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        1429-1440 of 1816 results for 'early childhood/'

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        Rare childhood diseases: how should we respond?

        Paradoxically, rare diseases are common, collectively affecting 6-10% of the population and have a huge impact on patients and families, health services,... ...

        Research

        Airway Epithelial Cell Immunity Is Delayed During Rhinovirus Infection in Asthma and COPD

        We propose that propensity for viral exacerbations of asthma and COPD relate to delayed expression of epithelial cell innate anti-viral immune genes ...

        Research

        Primary central nervous system lymphoma: Initial features, outcome, and late effects in 75 children and adolescents

        Children with Primary Central Nervous System Lymphoma and no immunodeficiency have a good outcome ...

        Research

        Relationship between cytokine expression patterns and clinical outcomes: two population-based birth cohorts

        Our findings suggest that positive HDM 'allergy tests' and asthma are associated with a broad range of immunophenotypes, which may have important... ...

        Research

        Phenotypic, functional, and plasticity features of classical and alternatively activated human macrophages

        Human peripheral blood monocytes were differentiated into uncommitted macrophages (M0) and then polarized to M1 and M2 phenotypes using LPS/IFN-gamma... ...

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        Infant nutrition and maternal obesity influence the risk of non-alcoholic fatty liver disease in adolescents

        We examined the association of maternal factors and infant nutrition, with the subsequent diagnosis of NAFLD in adolescents ...

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        Diet in the early years of life influences cognitive outcomes at 10 years: A prospective cohort study

        The aim of this study was to investigate the association between diet during the first 3 years of life and cognitive outcomes at 10 years of age. ...

        Research

        Asthma

        One in eight children have asthma, a chronic disease of the airways in the lungs. It results in shortness of breath, chest tightness, wheezing and coughing. ...

        Research

        Rationale, design and methods for the 22 year follow-up of the Western Australian Pregnancy Cohort (Raine) Study

        Young adulthood is a critical life period for health and health behaviours. ...

        Research

        Inhaled corticosteroids to improve lung function in children (aged 6–12 years) who were born very preterm (PICSI): a randomised, double-blind, placebo-controlled trial

        Despite the substantial burden of lung disease throughout childhood in children who were born very preterm, there are no evidence-based interventions to improve lung health beyond the neonatal period. We tested the hypothesis that inhaled corticosteroid improves lung function in this population. ...

        Research

        Murine bone-derived mesenchymal stem cells undergo molecular changes after a single passage in culture

        The rarity of the mesenchymal stem cell (MSC) population poses a significant challenge for MSC research. Therefore, these cells are often expanded in vitro, prior to use. However, long-term culture has been shown to alter primary MSC properties. ...

        Research

        Developing a prediction model to estimate the true burden of respiratory syncytial virus (RSV) in hospitalised children in Western Australia

        Respiratory syncytial virus (RSV) is a leading cause of childhood morbidity, however there is no systematic testing in children hospitalised with respiratory symptoms. Therefore, current RSV incidence likely underestimates the true burden. ...

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