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        Unusual paediatric spinal myxopapillary ependymomas: Unique molecular entities or pathological variations on a theme?

        We describe two unusual cases of MPE and use DNA methylation analyses to compare their signatures to try and distinguish if these represent a unique subset. ...

        Research

        Larger Than Life: Injecting Hope into the Planetary Health Paradigm

        We argue that the success of planetary health solutions is predicated on a more sophisticated understanding of the psychology of prevention and intervention at all scales ...

        Research

        Exploring factors impacting early childhood health among Aboriginal and Torres Strait Islander families and communities

        The impact of perinatal outcomes, maternal social and health outcomes and level of culturally secure service availability on the health outcomes of Western Australian Aboriginal infants and children ...

        Research

        Group A streptococcal pharyngitis: Immune responses involved in bacterial clearance and GAS-associated immunopathologies

        Innate and adaptive host immune responses are fundamental for defense against streptococcal pharyngitis and are central to the clinical manifestation of disease. ...

        Research

        Cohort profile: Pregnancy and childhood epigenetics (PACE) consortium

        Currently, DNA methylation is the most studied epigenetic phenomenon in large populations ...

        Research

        The school experiences of children and adolescents with type 1 diabetes in Western Australia

        Elevated levels of emotional difficulties among school students with T1D and variable levels of support from school staff to assist these students to manage their diabetes at school ...

        Research

        New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment

        We provide evidence that targeting leukemia-induced bone loss is a therapeutic strategy for pre-B ALL ...

        Research

        Association between male genital anomalies and adult male reproductive disorders: a population-based data linkage study spanning more than 40 years

        We provide new evidence to support current guidelines for orchidopexy before age 18 months to decrease the risk of future testicular cancer and infertility ...

        Research

        Improving delivery of secondary prophylaxis for rheumatic heart disease in a high-burden setting: Outcome of a stepped-wedge, community, randomized trial

        This strategy did not improve adherence to rheumatic heart disease secondary prophylaxis within the study time frame. ...

        Research

        Qualitative Evaluation of a Complex Intervention to Improve Rheumatic Heart Disease Secondary Prophylaxis

        A multifaceted intervention was implemented using quality improvement and chronic care model approaches to improve delivery of penicillin prophylaxis for rheumatic heart disease ...

        Research

        PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

        A novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis ...

        Research

        High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis

        High dose vitamin D supplementation is associated with a shift to a more inflammatory faecal microbiome and increased susceptibility to colitis ...

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