The gut microbiome changes in response to a range of environmental conditions, life events and disease states. Pregnancy is a natural life event that involves major physiological adaptation yet studies of the microbiome in pregnancy are limited and their findings inconsistent. Pregnancy with type 1 diabetes (T1D) is associated with increased maternal and fetal risks but the gut microbiome in this context has not been characterized. By whole metagenome sequencing, we defined the taxonomic composition and function of the gut bacterial microbiome across 70 pregnancies, 36 in women with T1D. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

To optimise fecal sampling for reproducible analysis of the gut microbiome, we compared different methods of sample collection and sequencing of 165 rRNA genes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• March 2018

To assess the effectiveness of antibiotics versus antiseptics for people with chronic suppurative otitis media. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

The burden of IgE-mediated food allergy in Australian born children is reported to be among the highest globally. This illness shares risk factors and frequently coexists with asthma, one of the most common noncommunicable diseases of childhood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

The EU LifeCycle Project was launched in 2017 to combine, harmonise, and analyse data from more than 250,000 participants across Europe and Australia, involving cohorts participating in the EU-funded LifeCycle Project. The purpose of this cohort description is to provide a detailed overview over the major measures within mental health domains that are available in 17 European and Australian cohorts participating in the LifeCycle Project. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

Collaboration between clinicians and researchers is required to establish the prevalence and disease burden of type 2 diabetes among Indigenous young people ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• February 2019

Very preterm infants have a marked innate inflammatory response at the time of late-onset sepsis ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Marked increases in maternal age and primiparous births were observed. A four-fold increase in the rates of pre-existing medical complications over time... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• August 2013

Relapse and acquired drug resistance in T-cell acute lymphoblastic leukemia (T-ALL) remains a significant clinical problem. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• August 2014

Interpregnancy intervals of <6 months were associated with increased odds of preterm birth in second-born infants ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

This study questions the causal effect of short interpregnancy intervals on adverse birth outcomes and points to the possibility of unmeasured or... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• July 2014

Our results indicate that an increase in the prelabour caesarean delivery rate for private patients in private hospitals has been driving the increase in the... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• May 2013