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        Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

        Acute erythroleukemia (AEL or acute myeloid leukemia [AML]-M6) is a rare but aggressive hematologic malignancy. Previous studies showed that AEL leukemic cells often carry complex karyotypes and mutations in known AML-associated oncogenes. ...

        Research

        Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?

        Baseline signatures might contribute to identifying interventional targets to be modulated prior to vaccination in order to improve vaccination responses ...

        Research

        Whole blood transcriptional responses of very preterm infants during late-onset sepsis

        Blood responses in very preterm infants with LOS are characterised by altered host immune responses that appear to reflect unbalanced immuno-metabolic homeostasis ...

        Research

        Reference exome data for Australian Aboriginal populations to support health-based research

        Our data set provides a useful reference point for genomic studies on Aboriginal Australians ...

        Research

        Progress in Model Systems of Cystic Fibrosis Mucosal Inflammation to Understand Aberrant Neutrophil Activity

        Here we examine the latest findings of neutrophils in pediatric CF lung disease and proposed mechanisms of their pathogenicity ...

        Research

        A novel, palatable paediatric oral formulation of midazolam: Pharmacokinetics, tolerability, efficacy and safety

        We conclude that the novel chocolate-based formulation of midazolam provides improved tolerability while remaining efficacious ...

        Research

        Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

        GWAS analyses of allergic sensitization against inhalant allergens and nonallergic rhinitis suggested shared genetic mechanisms across rhinitis-related traits ...

        Research

        Child-parent agreement on alcohol-related parenting: Opportunities for prevention of alcohol-related harm

        Parent non-supply of alcohol and disapproval of use were most important in terms of associations with ever drinking ...

        Research

        Reduced heart rate variability in a treatment-seeking early psychosis sample

        Findings provide preliminary evidence that early psychosis is associated with reduced heart rate variability ...

        Research

        Arylsulphatase A Pseudodeficiency (ARSA-PD), hypertension and chronic renal disease in Aboriginal Australians

        Traits associated with CVD, CRD and T2D in Aboriginal Australians provide novel insight into function of Arylsulphatase A Pseudodeficiency variants ...

        Research

        Motivational interviewing as a positive response to high-school bullying

        We provide a narrative review of Motivational Interviewing and map its core features onto the extant literature on self‐reported motivations for bullying ...

        Research

        Predictors of breastfeeding duration for rural women in a high-income country: Evidence from a cohort study

        Despite high breastfeeding initiation rates in Australia, few mothers exclusively breastfeed their infants to six months. This is particularly evident in... ...

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