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        Survival and mortality in cerebral palsy: Observations to the sixth decade from a data linkage study of a total population register and National Death Index

        Since 1990 mortality for those with severe cerebral palsy in Western Australia has tended to shift from childhood to early adulthood ...

        Research

        Epigenetic Age Acceleration in Adolescence Associates with BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease

        Accelerated epigenetic age in adolescence was associated with inflammation, BMI measured 5 years later, and probability of middle age cardiovascular disease ...

        Research

        The cellular effects of estrogen on allergic asthma

        Pat Deborah Holt Strickland PG DH PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic Program Patrick.Holt@telethonkids.org.au Deb.Strickland@telethonkids.org.au Emeritus Honorary ...

        Research

        Mechanisms of IgE sensitization

        Pat Deborah Holt Strickland PG DH PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic Program Patrick.Holt@telethonkids.org.au Deb.Strickland@telethonkids.org.au Emeritus Honorary ...

        Research

        Cystic Fibrosis

        Cystic fibrosis (CF) is the most common chronic, life-shortening genetic condition affecting young Australians. There is no cure but researchers are working to prevent the onset of lung disease. ...

        Research

        Psychometric properties of the Quality of Life Inventory-Disability (QI-Disability) measure

        Initial evaluation suggests that QI-Disability is a reliable and valid measure of quality of life across the spectrum of intellectual disability ...

        Research

        Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

        Combining elevated CRP with the presence or absence of clinical signs/ symptoms differentiates definite bacterial from presumed viral pneumonia better than CRP alone ...

        Research

        Australian Aboriginal children have higher hospitalization rates for otitis media but lower surgical procedures than non-Aboriginal children

        Aboriginal children and children from lower socio-economic backgrounds were over-represented with OM-related hospitalizations but had fewer TTIs ...

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        Quantification of Serum Ovalbumin-specific Immunoglobulin E Titre via in vivo Passive Cutaneous Anaphylaxis Assay

        We describe herein a highly reproducible in vivo passive cutaneous anaphylaxis assay using Sprague Dawley rats for the quantification of ovalbumin-specific IgE ...

        Research

        Planetary Health: From the Wellspring of Holistic Medicine to Personal and Public Health Imperative

        Here, we explore the history of planetary health and describe its relevance to contemporary healthcare ...

        Research

        Facilitators and Barriers of Participation in “Uptime” Activities in Girls and Women With Rett Syndrome: Perspectives From Parents and Professionals

        This study explored facilitators and barriers to "uptime" (non-sedentary) activities in Danish girls and women with Rett syndrome ...

        Research

        A Diagnosis for All Rare Genetic Diseases: The Horizon and the Next Frontiers

        There is a critical need for the field to develop and implement strategies to understand the mechanisms underlying all rare diseases and translate these to clinical care ...

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