Antifungal prophylaxis can reduce morbidity and mortality from invasive fungal disease (IFD). However, its use needs to be optimised and appropriately targeted to patients at highest risk to derive the most benefit. In addition to established risks for IFD, considerable recent progress in the treatment of malignancies has resulted in the development of new 'at-risk' groups. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

Aminoglycosides are commonly prescribed to children with febrile neutropenia (FN) but their impact on clinical outcomes is uncertain and extent of guideline compliance is unknown. We aimed to review aminoglycoside prescription and additional antibiotic prescribing, guideline compliance and outcomes for children with FN. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• September 2020

Research priority setting activities in paediatric chronic disease cover many discipline areas and have elicited a broad range of topics ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• October 2018

Influenza immunisation is a highly cost-effective public health intervention. Despite a comprehensive National Immunisation Program, influenza vaccination in children and adolescents with special risk medical conditions (SRMCs) is suboptimal. Flutext-4U is an innovative, multi-component strategy targeting paediatric hospitals, general practice and parents of children and adolescents with SRMC. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

The PCV7 was introduced to prevent IPD in WA Aboriginal people in 2001 to a lesser extent in older people. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• September 2017

This Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• December 2017

Pneumonia is the leading cause of death in young children globally and is prevalent in the Papua New Guinea highlands. We investigated clinical predictors of hypoxic pneumonia to inform local treatment guidelines in this resource-limited setting. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• April 2024

Are you listening? The inaugural OMOZ Workshop - towards a better understanding of otitis media ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• November 2010

Pat Peter Tom Holt Richmond Snelling PG PC T PhD, DSc, FRCPath, FRCPI, FAA MBBS MRCP(UK) FRACP BMBS DTMH GDipClinEpid PhD FRACP Emeritus Honorary Researcher Head, Vaccine Trials Group Head, Infectious Disease Implementation Research 08 6319 1817 ...

• 1. Telethon Kids Institute
• Projects

Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes an array of infectious diseases in humans. Accumulating clinical evidence suggests that proinflammatory interleukin (IL)-1beta signaling plays an important role in GAS disease progression. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

Nontypeable Haemophilus influenzae (NTHI) strains are responsible for respiratory-related infections which cause a significant burden of disease in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• February 2014