Unlike adults, malignant melanoma in children and adolescents is rare. In adult melanoma, significant progress in understanding tumor biology and new treatments, including targeted therapies and immunotherapy have markedly improved overall survival. In sharp contrast, there is a paucity of data on the biology and clinical behavior of pediatric melanoma. We report a national case series of all pediatric and adolescent malignant melanoma presenting to ANZCHOG Childhood Cancer Centers in Australia and New Zealand. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

To identify links between drug resistance and gene deregulation we used oligonucleotide microarray technology. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

The current study sought to increase our understanding of the factors involved in the early vocabulary development of Australian Indigenous children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014

The functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• July 2018

Ependymomas (EPN) are the third most common malignant brain cancer in children. Treatment strategies for pediatric EPN have remained unchanged over recent decades, with 10-year survival rates stagnating at just 67% for children aged 0-14 years. Moreover, a proportion of patients who survive treatment often suffer long-term neurological side effects as a result of therapy. It is evident that there is a need for safer, more effective treatments for pediatric EPN patients. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023

Despite low ERBB4 mRNA in glioblastoma, the functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• July 2018

Despite initial improvements in survival of infants with ALL since establishment of the first pediatric cooperative group ALL trials, the poor outcome has... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014

Recent research suggests that maternal folic acid supplementation is associated with a reduced risk of childhood brain tumors (CBT); polymorphisms in folate... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• March 2015

Nick Raelene Terrance Gottardo Endersby Johns NG R T MBChB FRACP PhD BSc (Hons) PhD Co-Head, Brain Tumour Research Brainchild Fellow; Co-Head, Brain Tumour Research Honorary Research Associate nicholas.gottardo@telethonkids.org.au raelene.endersby@ ...

• 1. Telethon Kids Institute
• Projects

Given the paucity of data concerning long-term outcome, the authors undertook a meta-analysis to analyze morbidity in survivors of this disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• September 2013

This study aimed to examine the pattern of stillbirth and neonatal mortality rate disparities over time in Western Australia ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

Leanne Robyn Karen Karen Sarah Fried Johnston Lombardi Forde Falconer LF RJ KL KF SF BSc DipEd MSpEd EdD BSc, Post Grad Dip, PhD BHSc (Hons), PhD BHlthSc (Hons 1A) BSc, MPH Senior Research Fellow Senior Research Officer Research Fellow Project ...

• 1. Telethon Kids Institute
• Projects