Visceral leishmaniasis (VL) caused by parasites of the Leishmania donovani complex can be fatal in susceptible individuals. Understanding the interactions between host and pathogen is one way to obtain leads to develop better drugs and for vaccine development. In recent years multiple omics-based approaches have assisted researchers to gain a more global picture of this interaction in leishmaniasis. Here we review results from studies using three omics-based approaches to study VL caused by L. donovani in India. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

We found transient pDC depletion during Pneumovirus infection alone predisposed to severe bronchiolitis in early life and subsequent asthma after reinfection. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• February 2018

Elevated levels of emotional difficulties among school students with T1D and variable levels of support from school staff to assist these students to manage their diabetes at school ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

The transforming growth factor-beta pathway is important in the immunopathogenesis of Visceral leishmaniasis ...

• 1. Telethon Kids Institute
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• Reports and Findings
• 2016
• January 2016

Here we employ whole blood assays to evaluate human cytokine responses to 11 of these antigens, in comparison to known defined and crude antigen preparations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

Mucosal leishmaniasis (ML) follows localized cutaneous leishmaniasis (CL) caused by Leishmania braziliensis. ...

• 1. Telethon Kids Institute
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• Reports and Findings
• 2010
• July 2010

This study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations. ...

• 1. Telethon Kids Institute
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• Reports and Findings
• 2010
• May 2010

On-time coverage of the 2-4-6 month schedule is only 50-60% across specific population subgroups representing a significant avoidable public health risk ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

This paper describes a mathematical model used to predict when an epidemic of respiratory syncytial virus (RSV) will occur so that preventive measures, such... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014

Reviewed in this article these studies have identified positive association at 21 genes with association at five of these replicated in independent populations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

Otitis media (OM) is a common childhood disease characterised by middle ear inflammation following infection ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• July 2011

Admissions for ARI were higher in Western Australia and displayed greater socioeconomic disparities than England and Scotland, where ARI rates are increasing ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019