Itraconazole remains a first-line antifungal agent for certain fungal infections in children, including allergic bronchopulmonary aspergillosis (ABPA) and sporotrichosis, but poor attainment of therapeutic drug levels is frequently observed with available oral formulations. A formulation of 'SUper BioAvailability itraconazole' (SUBA-itraconazole; Lozanoc®) has been developed, with adult studies demonstrating rapid and reliable attainment of therapeutic levels, yet paediatric data are lacking. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Large variation in antibiotic prescribing amongst clinicians is demonstrated and increased, corresponding with escalating case complexity and persisting MRSA bacteraemia ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

Recruitment of large numbers of pediatric pneumonia and meningitis cases and community controls in a third-world setting presents unique challenges ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• March 2017

Our findings are in line with a number of epidemiological studies which show a positive association between breastfeeding and OM in early childhood ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• February 2017

Systematic review of antibiotic duration and timing of intravenous to oral switch for paediatric infectious diseases and evidence-graded recommendations ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• August 2016

UVR or sunlight exposure may be an effective means of suppressing the development of obesity and MetS, through mechanisms that are independent of vitamin D ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• November 2014

Staphylococcus epidermidis is a nosocomial pathogen that causes catheter-associated bacteremia in the immunocompromised, including those at the extremes of age ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• April 2010

Hayley Andrea Christian Nathan HC AN BSc (1st Class Hons), PhD W.Aust. BHlthSc (hons), PhD Program Head, Healthy Behaviours and Environments; National Heart Foundation Future Leader Fellow Senior Research Officer, PLAYCE 08 6319 1040 +61 8 6319 1045 ...

• 1. Telethon Kids Institute
• Projects

Hayley Christian HC BSc (1st Class Hons), PhD W.Aust. Program Head, Healthy Behaviours and Environments; National Heart Foundation Future Leader Fellow 08 6319 1040 hayley.christian@telethonkids.org.au Program Head, Healthy Behaviours and ...

• 1. Telethon Kids Institute
• Projects
• Past projects

The highest incidence of sepsis across all age groups occurs in neonates leading to substantial mortality and morbidity. Cardiovascular dysfunction frequently complicates neonatal sepsis including biventricular systolic and/or diastolic dysfunction, vasoregulatory failure, and pulmonary arterial hypertension. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

A national collaboration was formed to provide longitudinal collection of T1D patient characteristics and outcomes, the Australasian Diabetes Data Network ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• August 2016

Functional role of CTGF in altering disease progression in a lymphoid malignancy ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016