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        The interaction between respiratory viruses and pathogenic bacteria

        Data on asymptomatic identification rates of respiratory viruses are limited, particularly in Indigenous populations, who suffer a high burden of OM. ...

        Research

        Unpacking the complex nature of the autism epidemic

        This paper discusses changes in diagnostic criteria, decreasing age at diagnosis, improved case ascertainment, diagnostic substitution, and social influences. ...

        Research

        Diverging trends for lower respiratory infections in non-Aboriginal and Aboriginal children

        To investigate temporal trends in admission rates for acute lower respiratory infections (ALRI) in a total population birth cohort of non-Aboriginal and... ...

        Research

        Does mum know best? Should we be vaccinating mothers to protect their babies from ear and lung disease?

        Elke Lea-Ann Ruth Peter Seppanen Kirkham Thornton Richmond ES LK RT PC BSc PhD PhD PhD MBBS MRCP(UK) FRACP Program Manager, Bacterial Respiratory Infectious Disease Group Co-Head, Bacterial Respiratory Infectious Disease Group; Microbiology Lead, ...

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        ORIGINS community wellbeing during the COVID-19 pandemic

        Desiree Jackie Lisa Susan Silva Davis Gibson Prescott DS JD LG SL MBBS, FRACP, MPH, PhD BSc (Hons) BA (Hons), MPsych, PhD MBBS BMedSci PhD FRACP Co-Head, The ORIGINS Project Co-Head, The ORIGINS Project Research Fellow, The ORIGINS Project Honorary ...

        Research

        The next generation of impact in cystic fibrosis

        Lung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment. ...

        Research

        An infant mouse model of influenza-driven nontypeable Haemophilus influenzae colonization and acute otitis media suitable for preclinical testing of novel therapies

        Nontypeable Haemophilus influenzae (NTHi) is a major otitis media (OM) pathogen, with colonization a prerequisite for disease development. Most acute OM is in children <5 years old, with recurrent and chronic OM impacting hearing and learning. Therapies to prevent NTHi colonization and/or disease are needed, especially for young children. Respiratory viruses are implicated in driving the development of bacterial OM in children. ...

        Research

        Skin Health in Northern Australia

        Achieving healthy skin requires the prevention of infectious diseases that affect the skin. Prevention activities range from environmental health improvements to address inequities in living situations, through to community-wide treatment programs to reduce transmission and improve skin health. ...

        Research

        The ORIGINS Project Biobank: A Collaborative Bio Resource for Investigating the Developmental Origins of Health and Disease

        Early onset Non-Communicable Diseases (NCDs), including obesity, allergies, and mental ill-health in childhood, present a serious and increasing threat to lifelong health and longevity. The ORIGINS Project (ORIGINS) addresses the urgent need for multidisciplinary efforts to understand the detrimental multisystem impacts of modern environments using well-curated large-scale longitudinal biological sample collections. ...

        Research

        From guidelines to practice: A retrospective clinical cohort study investigating implementation of the early detection guidelines for cerebral palsy in a state-wide early intervention service

        To report on knowledge translation strategies and outcomes from the implementation of the early detection guidelines for cerebral palsy (CP) in a state-wide tertiary early intervention (EI) service and investigate the impact of social determinants on clinical services. ...

        Research

        Evidence of maternal transfer of antigen-specific antibodies in serum and breast milk to infants at high-risk of S. pneumoniae and H. influenzae disease

        Children in low-mid income countries, and First Nations children in high-income countries, experience disproportionately high rates of Streptococcus pneumoniae and Haemophilus influenzae infections and diseases including pneumonia and otitis media. ...

        Research

        Modelling study of the ability to diagnose acute rheumatic fever at different levels of the Ugandan healthcare system

        To determine the ability to accurately diagnose acute rheumatic fever given the resources available at three levels of the Ugandan healthcare system. ...

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