We previously reported the efficacy of the adjuvanted-protein COVID-19 vaccine candidate S-Trimer (SCB-2019) in adults who showed no evidence of previous exposure to SARS-CoV-2. In this study, we aimed to investigate the extent of protection afforded by previous exposure to SARS-CoV-2 on subsequent COVID-19 infection, as well as the efficacy, safety, and reactogenicity of SCB-2019 in participants who were enrolled in the Study. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

Chemotherapy has historically been the mainstay of cancer treatment, but our understanding of what drives a successful therapeutic response remains limited. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

These data highlight the importance of recognising Sporotrichosis in children outside an outbreak setting ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020

A summary of the literature regarding the use of adjunctive protein synthesis inhibitors for toxin suppression in the setting of S. aureus infections is presented ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

Lung clearance index may be a useful surveillance tool to monitor structural lung disease in preschool and school-age children with cystic fibrosis ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

The prevalence of parent-reported rOM was 26.8% (611/2280) and 5.5% (125/2280) for severe rOM in the Study. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

Chris Deborah Peter Natasha Valerie Brennan-Jones Lehmann Richmond Morrison Swift C D PC NM VS PhD AO, MBBS, MSc MBBS MRCP(UK) FRACP Head, Ear Health Honorary Emeritus Fellow Head, Vaccine Trials Group Aboriginal Researcher Aboriginal Co-Director, ...

• 1. Telethon Kids Institute
• Projects

Here we focus on the problem of prioritising variants with respect to the observed disease phenotype ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

Otitis media (OM) is a common disease in early childhood characterised by inflammation of the middle ear. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

We identified several novel candidate genes which warrant further analysis in cohorts matched more precisely for clinical phenotypes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

Sébastien Laurence Rishi Sury Malinge Cheung Kotecha SM LC RS PhD BPharm (Hons) MBA PhD MB ChB (Hons) MRCPCH FRACP PhD Laboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior Research ...

• 1. Telethon Kids Institute
• Projects

IL7 and glucocorticoids coordinately drive aberrant activation of PIM1 and suggests that T-ALL and T-LBL patients could benefit from PIM inhibition ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020