The objective was to assess the glucagon response to hypoglycemia and identify influencing factors in patients with type 1 diabetes compared with nondiabetic... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• August 2012

Australian Aboriginal and Torres Strait Islander women with diabetes in pregnancy (DIP) are more likely to have glycaemic levels above the target range, and their babies are thus at higher risk of excessive fetal growth. Shoulder dystocia, defined by failure of spontaneous birth of fetal shoulder after birth of the head requiring obstetric maneuvers, is an obstetric emergency that is strongly associated with DIP and fetal size. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• May 2024

In response to DNA damaging chemotherapy, targeting MK2 in p53-mutated cells produces a phenotype that is distinct from the p53-deficient phenotype ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020

We present a curated panel of 12 readily-usable, cell lines representing the spectrum of molecular subtypes of IDH-wildtype glioblastoma ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

Accumulating evidence of the role of genetic variation in CP aetiology suggests that individuals with CP should undergo genomic testing as part of their diagnostic workup ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• February 2018

Measuring social inequalities in health is common; however, research examining inequalities in child cognitive function is more limited. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• October 2013

Fetal androgens influence fetal growth as well as postnatal neurocognitive ability ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• March 2010

Tim Barnett TB PhD Head of the Strep A Pathogenesis & Diagnostics team, Deputy Head of the Wesfarmers Centre of Vaccines and Infectious Diseases 6319 1319 timothy.barnett@telethonkids.org.au Head of the Strep A Pathogenesis & Diagnostics team, ...

• Telethon Kids Institute
• Projects

Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes an array of infectious diseases in humans. Accumulating clinical evidence suggests that proinflammatory interleukin (IL)-1beta signaling plays an important role in GAS disease progression. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

The climate crisis has detrimental impacts on the mental health and wellbeing of children and young people. Psychological effects include feelings of fear, overwhelm, worry, distress, hopelessness and anger; PTSD; depression; anxiety; phobias; panic disorder; sleep disturbances; attachment disorders; learning difficulties; substance abuse; shock and trauma symptoms; adjustment problems; behavioural problems; and, suicidal thinking. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

The COVID-19 pandemic has brought unprecedented levels of grief and psychological distress in community samples. We examined unique pandemic grief risk factors, dysfunctional grief, Post-traumatic Stress Disorder symptoms, general psychiatric distress, disrupted meaning, and functional impairment in a treatment-seeking sample of people bereaved from COVID-19 in the United Kingdom. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

Here we show that antibacterial activity of 4-hydroxy-2-heptylquinoline against Vibrionaceae is species-specific ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020