The respiratory outcomes for adult survivors of preterm birth in the postsurfactant era are wide-ranging with prognostic factors, especially those encountered after the neonatal period, poorly understood. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Children’s interstitial and diffuse lung disease (chILD) is a complex heterogeneous group of lung disorders. Gene panel approaches have a reported diagnostic yield of ~ 12%. No data currently exist using trio exome sequencing as the standard diagnostic modality. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Conserved vaccine candidate proteins from S.pneumoniae induce serum and salivary antibody responses in Aboriginal and non-Aboriginal children with history of OM ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

The European Respiratory Society Oscillometry Taskforce identified that clinical correlates of bronchodilator responses are needed to advance oscillometry in clinical practice. The understanding of bronchodilator-induced oscillometry changes in preterm lung disease is poor. Here we describe a comparison of bronchodilator assessments performed using oscillometry and spirometry in a population born very preterm and explore the relationship between bronchodilator-induced changes in respiratory function and clinical outcomes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

Pamela André Matt Laird Schultz Cooper PL AS MC Pictured (left to right) are the team working on the ACE project in the Pilbara region Darcy Roe - senior physiotherapist at Hedland Health Campus Anggun Effendy - senior physiotherapist at Hedland ...

• Telethon Kids Institute
• Projects

In children, the ratio of forced expiratory volume in 1 s (FEV₁) to forced vital capacity (FVC) is reportedly constant or falls linearly with age... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• December 2010

Chronic wet cough in children is the hallmark symptom of protracted bacterial bronchitis (PBB) and if left untreated can lead to bronchiectasis, which is prevalent in Indigenous populations. Underrecognition of chronic wet cough by parents and clinicians and underdiagnosis of PBB by clinicians are known. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Nontypeable Haemophilus influenzae (NTHi) is the most common bacterial otopathogen associated with otitis media (OM). NTHi persists in biofilms within the middle ears of children with chronic and recurrent OM. Australian Aboriginal children suffer exceptionally high rates of chronic and recurrent OM compared to non-Aboriginal children. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• April 2022

To assess the determinants of early lung function in African infants. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• May 2017

To investigate antimicrobial susceptibility of Moraxella catarrhalis isolated from a cohort of children being followed in a study of the natural history of OM ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• April 2010

We assessed the impact of PCV on all-cause and pathogen-specific pneumonia hospitalizations in Western Australian (WA) children aged 16 years. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• March 2018

Australian Aboriginal people have among the highest rates of invasive pneumococcal disease (IPD) worldwide. This paper investigates clinical diagnosis, risk... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• September 2014