Browse study websites

Discover. Prevent. Cure.

Menu Fundraise Donate

    Recommended pages

      Do you mean

        1669-1680 of 3501 results for 'development'

        Refine research

        Research

        Post-infectious group A streptococcal autoimmune syndromes and the heart

        ARF is a classical example of an autoimmune syndrome and is of particular immunological interest because it follows a known antecedent infection with group A... ...

        Research

        Does docosahexaenoic acid supplementation in term infants enhance neurocognitive functioning in infancy?

        The proposal that dietary docosahexaenoic acid (DHA) enhances neurocognitive functioning in term infants is controversial. ...

        Research

        Does gastrostomy improve the lives of children with severe disability and their families?

        Emma Helen Jenny Peter Glasson Leonard Downs Jacoby EJ HM JA PJ BPsych BSc (Hons) PhD MBChB MPH BApplSci (physio) MSc PhD BA (Hons) MSc Senior Research Fellow Principal Research Fellow Program Head, Development and Disability Biostatistician +61 ...

        Research

        The contribution of viruses and bacteria to community-acquired pneumonia in vaccinated children: A case - Control study

        Respiratory viruses, particularly respiratory syncytial virus and human metapneumovirus, are major contributors to pneumonia in Australian children ...

        Research

        Trends in prenatal diagnosis of congenital anomalies in Western Australia between 1980 and 2020: A population-based study

        Advances in screening and diagnostics have changed the way in which we identify and diagnose congenital anomalies. ...

        Research

        Pragmatic Adaptive Trial for Respiratory Infection in Children (PATRIC) Clinical Registry protocol

        Acute respiratory infections (ARI) are the most common cause of paediatric hospitalisation. There is an urgent need to address ongoing critical knowledge gaps in ARI management. The Pragmatic Adaptive Trial for Respiratory Infections in Children (PATRIC) Clinical Registry will evaluate current treatments and outcomes for ARI in a variety of paediatric patient groups. ...

        Research

        Epigenetics of the non-coding RNA nc886 across blood, adipose tissue and skeletal muscle in offspring exposed to diabetes in pregnancy

        Diabetes in pregnancy is associated with increased risk of long-term metabolic disease in the offspring, potentially mediated by in utero epigenetic variation. Previously, we identified multiple differentially methylated single CpG sites in offspring of women with gestational diabetes mellitus, but whether stretches of differentially methylated regions can also be identified in adolescent GDM offspring is unknown. ...

        Research

        Prenatal alcohol exposure and risk of birth defects

        The goal was to examine the associations between dose, pattern, and timing of prenatal alcohol exposure (PAE) and birth defects. ...

        Research

        Dual control of antitumor CD8 T cells through the programmed death-1/programmed death-ligand 1 pathway and immunosuppressive CD4 T cells

        Tumors have evolved multiple mechanisms to evade immune destruction. One of these is expression of T cell inhibitory ligands such as programmed death... ...

        Research

        Predictors of hospital readmission in infants less than 3 months old

        To examine rates and predictors of 7-day readmission in infants hospitalised before 3 months of age with infectious and non-infectious conditions. A retrospective population-based data-linkage study of 121 854 infants from a 5-year metropolitan birth cohort (2008-2012). Cox proportional hazard models were used to examine associations between infant and maternal factors with 7-day readmission. ...

        Research

        Exploring genotype-phenotype relationships in the CDKL5 deficiency disorder using an international dataset

        Characterized by early-onset seizures, global developmental delay and severe motor deficits, CDKL5 deficiency disorder is caused by pathogenic variants in the cyclin-dependent kinase-like 5 gene. Previous efforts to investigate genotype-phenotype relationships have been limited due to small numbers of recurrent mutations and small cohort sizes. Using data from the International CDKL5 Disorder Database we examined genotype-phenotype relationships for 13 recurrent CDKL5 variants and the previously analyzed historic variant groupings. We have applied the CDKL5 Developmental Score (CDS) and an adapted version of the CDKL5 Clinical Severity Assessment (CCSA), to grade the severity of phenotype and developmental outcomes for 285 individuals with CDKL5 variants. ...

        Research

        Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification

        We now have a growing number of epigenetic alterations in disease, and this offers a chance to increase sensitivity and specificity of future diagnostics and therapies ...

        Page 140 of 292