We have quantified the relative influence of perinatal risk factors associated with skin infection hospitalisations in WA children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• September 2019

Papua New Guinea (PNG) introduced the 13-valent pneumococcal conjugate vaccine (PCV13) in 2014, with administration at 1, 2, and 3 months of age. PCV13 has reduced or eliminated carriage of vaccine types in populations with low pneumococcal carriage prevalence, carriage density and serotype diversity. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

Alanna Mailing list media enquiries Sincovich Be Inspired Media Contacts AS Join thousands of active subscribers and hear about the brave kids, dedicated researchers, and world-leading science at Telethon Kids Institute. <!-- ----------------------- ...

• 1. Telethon Kids Institute
• Projects
• Past projects

Charlie Rebecca Christopher McLeod Pavlos Blyth CM RP CC MBBS (Hons), FRACP, PhD, DTM&H, DCH PhD, MSFS, MBBS (Hons) DCH FRACP FRCPA PhD Paediatric Infectious Diseases Clinician Researcher, Research Fellow, Raine Fellow, Deputy Director of the ...

• 1. Telethon Kids Institute
• Projects

Our goal was to identify genetic risk factors for severe otitis media (OM) in Aboriginal Australians. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

The recent increase in babies born with brain and eye malformations in Brazil is associated with Zika virus (ZIKV) infection in utero. ZIKV alters host DNA methylation in vitro. Using genome-wide DNA methylation profiling we compared 18 babies born with congenital ZIKV microcephaly with 20 controls. We found ZIKV-associated alteration of host methylation patterns, notably at RABGAP1L which is important in brain development, at viral host immunity genes MX1 and ISG15, and in an epigenetic module containing the causal microcephaly gene MCPH1. Our data support the hypothesis that clinical signs of congenital ZIKV are associated with changes in DNA methylation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

Our results show perturbation of host mitochondrial function following T. gondii infection that likely impacts on pathogenesis of disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• December 2017

IL8RA and IL8RB, encoded by CXCR1 and CXCR2, are receptors for interleukin (IL)-8 and other CXC chemokines involved in chemotaxis and activation of... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• December 2011

Otitis media (OM) is among the most common illnesses of early childhood, characterised by the presence of inflammation in the middle ear cavity... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• February 2011

The objective of this study was to describe the occurrence of skin infection associated hospitalizations in children born in Western Australia (WA). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Skin infections are a significant cause of severe disease, requiring hospitalization in Western Australian children, particularly with Aboriginal children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Rosemary Sophie Jonathan Wyber La Vincente Carapetis AM R SLV JR MBChB MPH FRACGP PhD BPsych (Hons) MAppEpi PhD AM MBBS FRACP FAFPHM PhD FAHMS Senior Research Fellow Rheach Deputy Director Executive Director; Head, Strep A Translation; Co-Founder of ...

• 1. Telethon Kids Institute
• Projects