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        1693-1704 of 1817 results for 'early childhood/'

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        Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India

        IL8RA and IL8RB, encoded by CXCR1 and CXCR2, are receptors for interleukin (IL)-8 and other CXC chemokines involved in chemotaxis and activation of... ...

        Research

        Common and Rare Genetic Variants That Could Contribute to Severe Otitis Media in an Australian Aboriginal Population

        Our goal was to identify genetic risk factors for severe otitis media (OM) in Aboriginal Australians. ...

        Research

        Toxoplasma gondii infection is associated with mitochondrial dysfunction in-vitro

        Our results show perturbation of host mitochondrial function following T. gondii infection that likely impacts on pathogenesis of disease. ...

        Research

        Evaluation of a bacterial therapy for prevention of respiratory infection including influenza and otitis media

        Deborah Jean-Francois Lea-Ann Peter Ruth Strickland Lauzon-Joset Kirkham Richmond Thornton DH JFLJ LK PC RT PhD PhD MBBS MRCP(UK) FRACP PhD Program Head, Immunobiology and Immunotherapeutic Program Senior Research Officer Co-Head, Bacterial ...

        Research

        The prevalence of mental health disorders and symptoms in children and adolescents with cerebral palsy: a systematic review and meta-analysis

        Mental health conditions and problems are often reported in children and adolescents with CP. A systematic review was undertaken to describe their prevalence. ...

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        An infant mouse model of influenza-driven nontypeable Haemophilus influenzae colonization and acute otitis media suitable for preclinical testing of novel therapies

        Nontypeable Haemophilus influenzae (NTHi) is a major otitis media (OM) pathogen, with colonization a prerequisite for disease development. Most acute OM is in children <5 years old, with recurrent and chronic OM impacting hearing and learning. Therapies to prevent NTHi colonization and/or disease are needed, especially for young children. Respiratory viruses are implicated in driving the development of bacterial OM in children. ...

        Research

        Ear Infections

        Middle ear infections are one of the main reasons that children visit a GP, are prescribed antibiotics and need surgery. Aboriginal children are particularly susceptible and commonly suffer from hearing loss which can affect speech and learning. ...

        Research

        Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study

        This genome-wide association study (GWAS) utilises data from the Western Australian Pregnancy Cohort (Raine) Study for 25-hydroxyvitamin D (25(OH)D) levels... ...

        Research

        DETECT Schools Study Protocol: A Prospective Observational Cohort Surveillance Study Investigating the Impact of COVID-19 in Western Australian Schools

        Amidst the evolving COVID-19 pandemic, understanding the transmission dynamics of the SARS-CoV-2 virus is key to providing peace of mind for the community and informing policy-making decisions. While available data suggest that school-aged children are not significant spreaders of SARS-CoV-2, the possibility of transmission in schools remains an ongoing concern, especially among an aging teaching workforce. Even in low-prevalence settings, communities must balance the potential risk of transmission with the need for students' ongoing education. ...

        Research

        Kids Easy Breathing Study

        André Timo Anthony Kathryn Peter Sam Alex Bep Thomas Schultz Lassmann Kicic Ramsey Richmond Buckberry Brown Uink Iosifidis AS T A KR PC SB AB BU TI MBChB, PhD, FRACP BSc (Hons) MSc PhD BSc (Hons) PhD BSc (Hons), PhD MBBS MRCP(UK) FRACP BSc, BHlthSc ...

        Research

        Barriers and enablers to promoting grandchildren’s physical activity and reducing screen time: a qualitative study with Australian grandparents

        With an increasing number of grandparents providing care to their grandchildren, calls have been made for these caregivers to be considered important stakeholders in encouraging children's engagement in health-promoting behaviors, such as physical activity. ...

        Research

        Childhood pneumonia in the Eastern Highlands Province of Papua New Guinea: clinical, microbiological and immunological predictors of disease

        Christopher Deborah Hannah Lea-Ann Peter Blyth Lehmann Moore Kirkham Richmond CC D HC LK PC MBBS (Hons) DCH FRACP FRCPA PhD AO, MBBS, MSc OAM BSc (Hons) GradDipClinEpi PhD PhD MBBS MRCP(UK) FRACP Director, Wesfarmers Centre of Vaccines and ...

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