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        1717-1728 of 1773 results for 'early life'

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        Population-based prevalence of intellectual disability and autism spectrum disorders in Western Australia

        The prevalence of intellectual disability has risen in WA over the last 10 years with most of this increase due to mild or moderate intellectual disability ...

        Research

        Young people with intellectual disability transitioning to adulthood: Do behaviour trajectories differ in those with and without down syndrome

        Changes in emotional and behavioural problems for young people with intellectual disability with and without Down syndrome as they transition into adulthood ...

        Research

        Autism risk associated with parental age and with increasing difference in age between the parents

        Increases in ASD was not only limited to advancing paternal or maternal age alone but also to differences parental age including younger or older similarly age ...

        Research

        Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3

        These findings implicate the activation of STAT3 as one pathway that may mediate resistance to IGF-II-targeted therapy in HCC ...

        Research

        Pregnancy and birth outcomes of mothers with intellectual disability and their infants: Advocacy needed to improve well-being

        For mothers with intellectual disability, modifiable risk factors for adverse outcomes need addressing ...

        Research

        A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma

        We present a curated panel of 12 readily-usable, cell lines representing the spectrum of molecular subtypes of IDH-wildtype glioblastoma ...

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        MK2 inhibition induces p53-dependent senescence in glioblastoma cells

        In response to DNA damaging chemotherapy, targeting MK2 in p53-mutated cells produces a phenotype that is distinct from the p53-deficient phenotype ...

        Research

        Validation of intellectual disability coding through hospital morbidity records using an intellectual disability population-based database in Western Australia

        To investigate how well intellectual disability (ID) can be ascertained using hospital morbidity data compared with a population-based data source. ...

        Research

        Association of Genetic and Environmental Factors with Autism in a 5-Country Cohort

        Based on population data from 5 countries, the heritability of ASD was estimated to be approximately 80% ...

        Research

        Birth seasonality and risk of autism spectrum disorder

        In the first multinational study of birth seasonality of autism spectrum disorder, there was evidence supporting the presence of seasonal trends in Finland and Sweden ...

        Research

        Feasibility of assessing diet with a mobile food record for adolescents and young adults with down syndrome

        The aim was to assess the feasibility of assessing diet with an image-based mobile food record application in 51 adolescents and young adults with Down syndrome. ...

        Research

        Improved Survival in Down Syndrome over the Last 60 Years and the Impact of Perinatal Factors in Recent Decades

        Improved survival for children born with Down syndrome over the last 60 years has occurred incrementally, but disparities still exist ...

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