In this chapter we present the research questions motivating the book and outline key themes and issues guiding the chapters. We provide a broad overview of the Australian social, political and economic context to give readers an understanding of some of the key features of Australian society. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

DNA methylation array profiling for classifying pediatric central nervous system (CNS) tumors is a valuable adjunct to histopathology. However, unbiased prospective and interlaboratory validation studies have been lacking. The AIM BRAIN diagnostic trial involving 11 pediatric cancer centers in Australia and New Zealand. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

There is insufficient evidence available to determine whether these organisms are pathogens, commensals or contribute indirectly to the pathogenesis of OM ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

The ANZCHOG-BN was developed to improve and streamline access to high quality pediatric and adolescent/young adult cancer biospecimens for cancer research ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

Among Aboriginal children, the burden of acute respiratory tract infections (ALRIs) with consequent bronchiectasis post-hospitalisation is high. Clinical practice guidelines recommend medical follow-up one-month following discharge, which provides an opportunity to screen and manage persistent symptoms and may prevent bronchiectasis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

Transcription of the human mitochondrial genome and correct processing of the two long polycistronic transcripts are crucial for oxidative phosphorylation. According to the tRNA punctuation model, nucleolytic processing of these large precursor transcripts occurs mainly through the excision of the tRNAs that flank most rRNAs and mRNAs. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

This article identifies and examines a range of policy reform opportunities in Australia arising from COVID-19. The authors demonstrate how COVID-19 presents unique opportunities for rethinking and redesigning long-standing rules and regulations covering how people live and work in Australia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Sarcomeric gene mutations are associated with the development of hypertrophic cardiomyopathy (HCM). Current drug therapeutics for HCM patients are effective in relieving symptoms, but do not prevent or reverse disease progression. Moreover, due to heterogeneity in the clinical manifestations of the disease, patients experience variable outcomes in response to therapeutics. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

Evaluation of a group parenting programme in the Northern Territory of Australia showed significant differences in benefits for Aboriginal and non-Aboriginal... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

Mothers of children diagnosed with cancer have been shown to experience high rates of psychological distress and poor physical health. Pregnancy further increases the healthcare needs of mothers due to the marked physiological changes and psychological adaptations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022

To test the fit of a seven-syndrome model to ratings of preschoolers' problems by parents in very diverse societies. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• December 2010