Children typically experience more mild symptoms of Coronavirus Disease 2019 (COVID-19) when compared to adults. There is a strong body of evidence that children are also less susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection with the ancestral viral isolate. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022

Modulation of ASL pH has been proposed as a therapy for CF. However, evidence that ASL pH is reduced in CF is limited and conflicting. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Pneumococcal surface protein A is immunogenic and natural anti-PspA immune responses are acquired through exposure and develop with age ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• August 2016

Background: We assessed the effect of posture on ventilation distribution and the impact on associations with structural lung disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Lung function trajectories are impaired in survivors of very preterm birth ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

Kathryn André Yuliya Alana Ramsey Schultz Karpievitch Harper KR AS YK AH BSc (Hons), PhD MBChB, PhD, FRACP PhD, MS, BS BSc (hons) Co-Head, Children's Lung Health Program Head, Respiratory Health RFA Ai and Data Analytics Lead, Respiratory Research ...

• 1. Telethon Kids Institute
• Projects

ATP Binding Cassette Subfamily A Member 3 (ABCA-3) is a lipid transporter protein highly expressed in type-II alveolar (AT-II) cells. Mutations in ABCA3 can result in severe respiratory disease in infants and children. To study ABCA-3 deficiency in vitro, primary AT-II cells would be the cell culture of choice although sample accessibility is limited. Our aim was to investigate the suitability of primary nasal epithelial cells, as a surrogate culture model for AT-II cells, to study ABCA-3 deficiency. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

Middle ear infections are one of the main reasons that children visit a GP, are prescribed antibiotics and need surgery. Aboriginal children are particularly susceptible and commonly suffer from hearing loss which can affect speech and learning. ...

• 1. Telethon Kids Institute
• Our research
• Research Topics

Lung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment. ...

• 1. Telethon Kids Institute
• Projects

Stephen Graham Elizabeth Stick Hall Smith SM GL ES MB BChir PhD MRCP FRACP BAppSci PhD CRFS FANZSRS FThorSoc FERS PhD, MSc, BSc Head, P4 Respiratory Health for Kids Honorary Research Associate Program Manager 08 6319 1178 elizabeth.smith@ ...

• 1. Telethon Kids Institute
• Projects

Ventilated preterm infant lungs are vulnerable to overdistension and underinflation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Non-invasive techniques for measuring lung mechanics in infants are needed for a better understanding of lung growth and function... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015