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        169-180 of 671 results for 'early childhood education'

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        Substrate-dependent metabolomic signatures of myeloperoxidase activity in airway epithelial cells: Implications for early cystic fibrosis lung disease

        Myeloperoxidase is released by neutrophils in inflamed tissues. MPO oxidizes chloride, bromide, and thiocyanate to produce hypochlorous acid, hypobromous acid, and hypothiocyanous acid, respectively. These oxidants are toxic to pathogens, but may also react with host cells to elicit biological activity and potential toxicity. In cystic fibrosis and related diseases, increased neutrophil inflammation leads to increased airway MPO and airway epithelial cell exposure to its oxidants. ...

        Research

        Cystic fibrosis clinical isolates of aspergillus fumigatus induce similar muco-inflammatory responses in primary airway epithelial cells

        Aspergillus is increasingly associated with lung inflammation and mucus plugging in early cystic fibrosis disease during which conidia burden is low and strains appear to be highly diverse. It is unknown whether clinical Aspergillus strains vary in their capacity to induce epithelial inflammation and mucus production. ...

        Research

        Playgroups

        The importance of play for a child’s development is irrefutable. Playgroups provide a safe environment for children of similar ages to play and develop prior to starting school. ...

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        Early motor function of children with autism spectrum disorder: A systematic review

        Early motor impairments have been reported in children with neurodevelopmental disorders (NDD), but it is not clear if early detection of motor impairments can identify children at risk for NDD or how early such impairments might be detected. Our aim was to characterize early motor function in children later diagnosed with NDD relative to typically developing children or normative data. ...

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        The Effects of Interpregnancy Intervals, Family Size & Sociodemographic Factors on Child Development Outcomes at Age 5

        Hayley Melissa Christian O'Donnell HC M BSc (1st Class Hons), PhD W.Aust. BPsych (Hons), MPsych, GradDip Ed, PhD Program Head, Healthy Behaviours and Environments; National Heart Foundation Future Leader Fellow Honorary Research Associate 08 6319 ...

        Research

        Associations between School Readiness and Student Wellbeing: A Six-Year Follow Up Study

        It is well established that children’s school readiness is associated with their later academic achievement, but less is known about whether school readiness is also associated with other measures of school success, such as students’ social and emotional wellbeing. While some previous research has shown a link between early social and emotional development and student wellbeing, results are mixed and the strength of these relationships vary depending on whether data is based on child, teachers or parents ratings and which specific student wellbeing outcomes are measured. ...

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        CFC Report

        Download Investigators: Cate Taylor, Daniel Christensen Partners: Tasmanian Early Years Foundation The Tasmanian Government has made a significant commitment in recent years to ensure children have the best possible start in life. However, the cycle ...

        Research

        Pathways into Noncommunicable Diseases Start Early in Life. In: Sykes H, Blashki G, editors. Dancing in the Rain

        We are living in a time of unprecedented risk for noncommunicable diseases (NCDs), such as obesity, cardiovascular disease, diabetes, cancer... ...

        Research

        Longitudinal effects of dog ownership, dog acquisition, and dog loss on children’s movement behaviours: findings from the PLAYCE cohort study

        Regular physical activity is important for children's physical and mental health, yet many children do not achieve recommended amounts of physical activity. Dog ownership has been associated with increased physical activity in children, however, there have been no longitudinal studies examining this relationship. ...

        Research

        Knowing your audience: Investigating stillbirth knowledge and perceptions in the general population to inform future public health campaigns

        The prevalence of stillbirth in many high income countries like Australia has remained unchanged for over 30 years. The 2018 Australian government Senate Select Committee on Stillbirth Research and Education highlighted the need for a public health campaign to encourage public conversations and increase awareness. ...

        Research

        Defective function at the epithelial junction: A novel therapeutic frontier in asthma?

        The airway epithelium forms a highly regulated physical barrier that normally prevents invasion of inhaled pathogens and allergens from the airway lumen. ...

        Research

        Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis Patients

        Cystic fibrosis (CF) is a congenital disorder resulting in a multisystemic impairment in ion homeostasis. The subsequent alteration of electrochemical gradients severely compromises the function of the airway epithelia. ...

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