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        1825-1836 of 3501 results for 'development'

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        RE-AIM Evaluation of the Alcohol and Pregnancy Project: Educational Resources to Inform Health Professionals

        The objective was to evaluate the Alcohol and Pregnancy Project that provided health professionals in Western Australia (WA) with educational resources ...

        Research

        The Second Research Report: patterns and trends in mortality of Western Australian infants, children and young people 2004-2005

        This report was commissioned by the Department for Child Protection as an ongoing initiative to continue the work initiated by researchers at the Telethon Kids ...

        Research

        CONNECT – Collaborative Network for Neuro-oncology Clinical Trials

        Raelene Endersby R BSc (Hons) PhD Brainchild Fellow; Co-Head, Brain Tumour Research raelene.endersby@telethonkids.org.au Co-Head, Brain Tumour Research Raelene was awarded her PhD in 2003 from the Harry Perkins Institute for Medical Research (under ...

        Research

        DETECT Schools

        The DETECT-Schools Study was launched in May 2020 as a partnership between the WA Government Departments of Education and Health with the Telethon Kids Institute.  ...

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        Determining the off-target effects of infant vaccines on respiratory infection outcomes in Western Australian children

        Christopher Hannah Lea-Ann Blyth Moore Kirkham CC HC LK MBBS (Hons) DCH FRACP FRCPA PhD OAM BSc (Hons) GradDipClinEpi PhD PhD Centre Head, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases Epidemiology, Wesfarmers ...

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        Transition to parenting

        Amy Finlay-Jones AFJ BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) Head, Early Neurodevelopment & Mental Health; Healthway WA Senior Research Fellow +61 8 6319 1808 amy.finlay-jones@telethonkids.org.au Head, Early Neurodevelopment & ...

        Research

        Retinopathy of prematurity and placental histopathology findings: A retrospective cohort study

        Retinopathy of prematurity (ROP) is a biphasic vaso-proliferative disease that has the potential to cause blindness. In addition to prematurity and hyperoxia, perinatal infection and inflammation have been reported to play a critical role in the pathogenesis of ROP. The aim of this study was to assess the association between placental inflammation and the severity of ROP. ...

        Research

        Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in supratentorial ependymoma

        Supratentorial RELA fusion (ST-RELA) ependymomas (EPNs) are resistant tumors without an approved chemotherapeutic treatment. Unfortunately, the molecular mechanisms that lead to chemoresistance traits of ST-RELA remain elusive. The aim of this study was to assess RELA fusion-dependent signaling modules, specifically the role of the Hedgehog (Hh) pathway as a novel targetable vulnerability in ST-RELA. ...

        Research

        Genetic counseling as preventive intervention: toward individual specification of transgenerational autism risk

        Although autism spectrum disorders (ASD) are among the most heritable of all neuropsychiatric syndromes, most affected children are born to unaffected parents. Recently, we reported an average increase of 3-5% over general population risk of ASD among offspring of adults who have first-degree relatives with ASD in a large epidemiologic family sample. ...

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        The orofacial, oromotor, speech, and voice characteristics of adolescents in youth detention: a comparison of groups with and without prenatal alcohol exposure

        Language disorder is highly prevalent in youth justice; however, orofacial, oromotor, speech, and voice anomalies have been largely overlooked. There has been some documentation of these among individuals with prenatal alcohol exposure (PAE), and adolescents with PAE are over-represented in youth justice. ...

        Research

        Parents' experiences of children with a rare disease attending a mainstream school: Australia

        To explore the perceptions of parents who had a child or adolescent (6-18 years) diagnosed with a rare disease who attended a mainstream school in Western Australia. Design and methods: A cross-sectional online survey was conducted with 41 parents of children with a rare disease. ...

        Research

        Age of Diagnosis for Co-occurring Autism and Attention Deficit Hyperactivity Disorder During Childhood and Adolescence: a Systematic Review

        Early identification and intervention are recognised as important elements of the clinical pathway for autism spectrum disorder (ASD). Children with ASD and attention deficit hyperactivity disorder (ADHD) may be diagnosed at a different age than children who only have one of these diagnoses. ...

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