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        1861-1872 of 3501 results for 'development'

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        Childhood pneumonia and meningitis in the Eastern Highlands Province, Papua New Guinea in the era of conjugate vaccines: study methods and challenges

        Recruitment of large numbers of pediatric pneumonia and meningitis cases and community controls in a third-world setting presents unique challenges ...

        Research

        A randomised controlled trial of an iPad-based application to complement early behavioural intervention in Autism Spectrum Disorder

        Technology-based interventions may provide a relatively low-cost addition to existing therapist-delivered interventions for children with ASD ...

        Research

        Using record linkage to validate notification and laboratory data for a more accurate assessment of notifiable infectious diseases

        Studies investigating pathogen-specific infectious disease would benefit from using multiple data sources. ...

        Research

        Antibiotic duration and timing of the switch from intravenous to oral route for bacterial infections in children: systematic review and guidelines

        Systematic review of antibiotic duration and timing of intravenous to oral switch for paediatric infectious diseases and evidence-graded recommendations ...

        Research

        Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries

        These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development. ...

        Research

        The course and prognostic capability of motor difficulties in infants showing early signs of autism

        Delays within the motor domain are often overlooked as an early surveillance marker for autism. The present study evaluated motor difficulties and its potential as an early predictive marker for later autism likelihood in a cohort of infants showing early behavioral signs of autism aged 9-14 months. The motor domain was evaluated using the motor subscales of the Mullen Scales of Early Learning at baseline, and at a 6-month follow-up. ...

        Research

        Assessing the burden of laboratory-confirmed respiratory syncytial virus infection in a population cohort of Australian children through record linkage

        Respiratory syncytial virus is pervasive across multiple severity levels and diagnoses. Vaccines targeting children <3 months must be prioritized ...

        Research

        Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school-aged children

        The expression pattern of FcεRI on DC and basophils differentiates asthmatic from non-asthmatic atopic children ...

        Research

        Infectious diseases clinician's variation in the management of pediatric Staphylococcus aureus bacteraemia and equipoise for clinical trials

        Large variation in antibiotic prescribing amongst clinicians is demonstrated and increased, corresponding with escalating case complexity and persisting MRSA bacteraemia ...

        Research

        Clinical experience with SUBA-itraconazole at a tertiary paediatric hospital

        Itraconazole remains a first-line antifungal agent for certain fungal infections in children, including allergic bronchopulmonary aspergillosis (ABPA) and sporotrichosis, but poor attainment of therapeutic drug levels is frequently observed with available oral formulations. A formulation of 'SUper BioAvailability itraconazole' (SUBA-itraconazole; Lozanoc®) has been developed, with adult studies demonstrating rapid and reliable attainment of therapeutic levels, yet paediatric data are lacking. ...

        Research

        Mums Minds Matter

        Amy Jenny Susan Desiree Keerthi Finlay-Jones Downs Prescott Silva Kottampally AFJ JA SL DS KK BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) BApplSci (physio) MSc PhD MBBS BMedSci PhD FRACP MBBS, FRACP, MPH, PhD Bsc (Hons), ...

        Research

        Epidemiology of gastrostomy insertion for children and adolescents with intellectual disability

        Gastrostomy is increasingly used in multiple neurological conditions associated with intellectual disability, with no apparent accessibility barriers ...

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