Recurrences frequently occur following surgical removal of primary tumors. In many cancers, adjuvant therapies have limited efficacy. Surgery provides access to the tumor microenvironment, creating an opportunity for local therapy, in particular immunotherapy, which can induce local and systemic anti-cancer effects. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

The effect of prenatal marijuana exposure on child neurodevelopment remains poorly understood. Prior studies have demonstrated inconsistent results. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• Jun 2023

Neutrophils are the most abundant immune cell in circulation. However, due to a number of technical challenges for researchers, including the neutrophil's short lifespan and difficulties with preservation, they are often discarded during blood processing and thus ignored in cohort studies. As such, the contribution of neutrophils to disease and their involvement in disease mechanisms is less explored compared with other immune cell types. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

Despite evidence supporting earlier discharge of well-appearing febrile infants at low risk of serious bacterial infection (SBI), admissions for ≥48 hours remain common. Prospective safety monitoring may support broader guideline implementation. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• September 2023

Although eye abnormalities are reported in fetal alcohol spectrum disorders (FASD), no systematic review based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines has been undertaken. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

The media plays a powerful role in shaping health-related attitudes and behaviours. We investigated media reports about children's independent mobility (CIM) and associations with parental attitudes towards CIM. CIM-related media reports (newspaper, online, television) during a 3-month period were extracted from two databases. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022

Rapid facial reactions to emotional stimuli are intact in late adulthood, even in response to stimuli that activate more automatic and implicit forms of emotion processing ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

This community partnered pilot research, evaluated a school-based program to reduce the behavioral impact of fetal alcohol spectrum disorder ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

Maternal immune activation and prenatal maternal stress are well-studied risk factors for psychiatric conditions such as autism and schizophrenia. Animal studies have proposed the gut microbiome as a mechanism underlying this association and have found that risk factor-related gut microbiome alterations persist in the adult offspring. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• August 2024

The new diagnostic category of disruptive mood dysregulation disorder (DMDD) was introduced in DSM-5 ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Consideration of expanded carrier screening has become an emerging issue for governments. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• February 2017

The results suggest that though the risk for RSV in the NICU remains low, personnel clothing are contaminated with RSV-RNA and may have a role in transmission ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016