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        181-192 of 418 results for 'END RHD'

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        Evaluating the role of asymptomatic throat carriage of Streptococcus pyogenes in impetigo transmission in remote Aboriginal communities in Northern Territory, Australia: a retrospective genomic analysis

        Streptococcus pyogenes, or group A Streptococcus (GAS), infections contribute to a high burden of disease in Aboriginal Australians, causing skin infections and immune sequelae such as rheumatic heart disease. Controlling skin infections in these populations has proven difficult, with transmission dynamics being poorly understood. We aimed to identify the relative contributions of impetigo and asymptomatic throat carriage to GAS transmission. ...

        Research

        Starting the SToP trial: Lessons from a collaborative recruitment approach

        Recruitment in research can be challenging in Australian Aboriginal contexts. We aimed to evaluate the SToP (See, Treat, Prevent skin infections) trial recruitment approach for Aboriginal families to identify barriers and facilitators and understand the utility of the visual resource used. ...

        Research

        The inequitable burden of group A streptococcal diseases in Indigenous Australians

        Given the ongoing mortality and morbidity from GAS infections, we must address more effectively the treatment and prevention of GAS impetigo and pharyngitis ...

        Research

        Standardising and assessing digital images for use in clinical trials: A practical, reproducible method that blinds the assessor to treatment allocation

        We describe the development and evaluation of a protocol for digital image collection by the non-professional photographer in a remote setting research trial ...

        Research

        Screening for rheumatic heart disease: Quality and agreement of focused cardiac ultrasound by briefly trained health workers

        After brief training, health workers with no prior experience in echocardiography can obtain adequate quality images and make a reliable assessment ...

        Research

        Searching for a technology-driven acute rheumatic fever test: the START study protocol

        The absence of a diagnostic test for acute rheumatic fever (ARF) is a major impediment in managing this serious childhood condition. ARF is an autoimmune condition triggered by infection with group A Streptococcus. ...

        Research

        National Healthy Skin Guideline; for the Prevention, Treatment and Public Health Control of Impetigo, Scabies, Crusted Scabies and Tinea for Indigenous Populations and Communities in Australia

        Asha Jonathan Marianne Bowen Carapetis AM Mullane AC JR MM BA MBBS DCH FRACP PhD GAICD OAM AM MBBS FRACP FAFPHM PhD FAHMS BSc (OT) Head, Healthy Skin and ARF Prevention Executive Director; Head, Strep A Translation; Co-Founder of REACH Program ...

        Research

        The microbiology of impetigo in Indigenous children

        Prevalence and antimicrobial resistance of impetigo pathogens in a randomised, controlled trial of impetigo treatment conducted in remote Indigenous communities ...

        Research

        Outcomes of rheumatic fever in Uganda: a prospective cohort study

        Rheumatic heart disease is the largest contributor to cardiac-related mortality in children worldwide. Outcomes in endemic settings after its antecedent illness, acute rheumatic fever, are not well understood. We aimed to describe 3-5 year mortality, acute rheumatic fever recurrence, changes in carditis, and correlates of mortality after acute rheumatic fever.  ...

        Research

        Investigation of trimethoprim/sulfamethoxazole resistance in an emerging sequence type 5 methicillin-resistant Staphylococcus aureus clone reveals discrepant resistance reporting

        Our findings are crucial in demonstrating that the Northern Territory STS clone is not STX resistant ...

        Research

        Comparison of three methods for the recovery of skin pathogens from impetigo swabs collected in a remote community of Northern Territory, Australia

        Immediate plating of impetigo swabs is the gold standard for bacterial recovery but is rarely feasible in remote regions. ...

        Research

        Ascertaining infectious disease burden through primary care clinic attendance among young Aboriginal children living in four remote communities in Western Australia

        Improved public health measures targeting bacterial skin infections are needed to reduce this high burden of skin infections in Western Australia ...

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