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        181-192 of 785 results for 'asthma'

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        Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life

        Appropriate innate immune function is essential to limit pathogenesis and severity of severe lower respiratory infections (sLRI) during infancy, a leading cause of hospitalization and risk factor for subsequent asthma in this age group. ...

        Research

        T-cell responses against rhinovirus species A and C in asthmatic and healthy children

        Infections by RV species A and C are the most common causes of exacerbations of asthma and a major cause of exacerbations of other respiratory disease. ...

        Research

        Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM-85

        The effects of OM-85 were strongest in the first winter season, with a trend for fewer children in the OM-85 group to have sLRIs and URIs ...

        Research

        Foetal growth restriction in mice modifies postnatal airway responsiveness in an age and sex-dependent manner

        Our data demonstrate changes in airway responsiveness as a result of intrauterine growth restriction that could influence susceptibility to asthma development ...

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        Cord-blood respiratory syncytial virus antibodies and respiratory health in first 5 years of life

        To determine the potential longer-term effects of maternal antenatal respiratory syncytial virus (RSV) vaccination, we examined the association between cord-blood RSV-neutralizing antibodies (RSV-NA) and RSV infections in the first 2 years of life, RSV-NA at 3 years, and respiratory health to age 5 years. ...

        Research

        Pressurised metered dose inhaler-spacer technique in young children improves with video instruction

        Repeated video instruction over time improves inhaler technique in young children ...

        Research

        QuantSeq. 3′ Sequencing combined with Salmon provides a fast, reliable approach for high throughput RNA expression analysis

        QuantSeq, coupled with a fast quantification method such as Salmon, should provide a viable alternative to traditional RNA-Seq in many applications ...

        Research

        Risk factors and prognosis of recurrent wheezing in Chinese young children: A prospective cohort study

        We aimed to investigate the risk factors for different wheezing phenotypes in Chinese young children and to explore the prognosis of recurrent wheezing ...

        Research

        No simple answers for the Finnish and Russian Karelia allergy contrast: Methylation of CD14 gene

        The methylation variation in the promoter region of CD14 gene did not explain the asthma and allergy contrast between Finnish and Russian Karelian children ...

        Research

        Protection against severe infant lower respiratory tract infections by immune training: Mechanistic studies

        Results from recent clinical studies suggest potential efficacy of immune training (IT)-based approaches for protection against severe lower respiratory tract infections in infants, but underlying mechanisms are unclear. ...

        Research

        Functional differences in airway dendritic cells determine susceptibility to IgE-sensitization

        Respiratory IgE-sensitization to innocuous antigens increases the risk for developing diseases such as allergic asthma. ...

        Research

        Environment Changes Genetic Effects on Respiratory Conditions and Allergic Phenotypes

        Genotype-phenotype associations relating to bronchitis and allergy susceptibility are dependent on the environment ...

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