Jonathan Michael Tobias Carapetis AM Serralha Kollmann JR MS TK AM MBBS FRACP FAFPHM PhD FAHMS PhD, M.D., SFUW Executive Director; Head, Strep A Translation; Co-Founder of REACH Research Assistant Honorary Research Associate 08 6319 1000 08 6319 ...

• 1. Telethon Kids Institute
• Projects

Surgical intervention is an important treatment modality for advanced rheumatic heart disease (RHD). This study aimed to describe patient characteristics and outcomes from cardiac surgery for RHD in patients referred to the only tertiary paediatric hospital in Western Australia.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

Acute rheumatic fever (ARF), an autoimmune reaction to Group A Streptococcus (Streptococcus pyogenes; Strep A) infection, can cause rheumatic heart disease (RHD). New formulations of long-acting penicillins are being developed for secondary prophylaxis of ARF and RHD. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

This study will identify the incidence of true Group A Streptococcal pharyngitis and serological responses to Group A Streptococcal GAS skin infections ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

Prevention strategies in ARF endemic settings may be enhanced by targeting new members entering a community and children in environments of close contact ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

We propose that hydroxychloroquine could be repurposed to reduce the risk of rheumatic heart disease after acute rheumatic fever ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

Echocardiographic screening for rheumatic heart disease (RHD) can identify individuals with subclinical disease who could benefit from antibiotic prophylaxis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• June 2016

Develop a 'roadmap' of key actions that need to be taken by governments to eliminate ARF and eradicate RHD in Africa ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• May 2016

We review GAS transmission characteristics and prevention strategies, historical and geographical trends and report on the estimated global burden disease... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au Institute Director; Head, Strep A Translation; Co-Founder of REACH Professor ...

• 1. Telethon Kids Institute
• Projects

This review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• April 2017

Adverse outcomes for people with acute rheumatic fever and rheumatic heart disease and the effect of comorbidities and demographic factors on these outcomes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• July 2016