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        Childhood Overweight and Obesity: Maternal and Family Factors

        The need to target prevention and intervention efforts for childhood overweight and obesity towards families with overweight parents ...

        Research

        Glycemia, Treatment Satisfaction, Cognition, and Sleep Quality in Adults and Adolescents with Type 1 Diabetes When Using a Closed-Loop System

        Android-HCLS in both adults and adolescents reduced nocturnal hypoglycemia and, in adults, improved overnight time in target range and treatment satisfaction ...

        Research

        Are low sun exposure and/or Vitamin D risk factors for type 1 diabetes

        Evidence supports that higher sun exposure and/or vitamin D sufficiency in pregnancy, or supplementation in early life, decreases type 1 diabetes risk ...

        Research

        Glucose Concentrations of Less Than 3.0 mmol/L (54 mg/dL) Should Be Reported in Clinical Trials: A Joint Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes

        The IHSG recommends that the frequency of detection of a glucose concentration <3.0mmol/L, to be included in clinical trial reports of glucose lowering drugs. ...

        Research

        Exercise training improves vascular function in adolescents with type 2 diabetes

        Exercise training can improve both endothelial function and health, independent of changes in insulin sensitivity in adolescents with type 2 diabetes ...

        Research

        Validation of Physical Activity Assessment in Type 1 Diabetes – an Essential Step to Incorporating Systematic Measurement of Activity as the Standard of Care in Youth

        Liz Tim Davis Jones EA TW MBBS FRACP PhD MBBS DCH FRACP MD Head, Chronic & Severe Diseases Research Focus Area; Clinical Lead, Diabetes and Obesity Research Co-head, Diabetes and Obesity Research Head, Chronic & Severe Diseases Research Focus Area; ...

        Research

        Standardised mortality is increased three-fold in a population-based sample of children and adolescents with type 1 diabetes

        Fatalities in children and adolescents (1-17 yr) with T1DM were identified from the Western Australia Children's Diabetes Database between 1987-2011. ...

        Research

        Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors

        Epigenetics links perinatal influences with later obesity. We identifed differentially methylated CpG (dmCpG) loci measured at 17 years associated with concurrent adiposity measures and examined whether these were associated with hsCRP, adipokines, and early life environmental factors. Genome-wide DNA methylation from 1192 Raine Study participants at 17 years, identified 29 dmCpGs associated with body mass index, 10 with waist circumference and 9 with subcutaneous fat thickness. ...

        Research

        Use of linked administrative and laboratory data to confirm that serum 25(OH)D levels in pregnant women can be predicted from satellite estimates of ultraviolet radiation

        Serum 25 hydroxyvitamin D [25(OH)D] levels of pregnant women have been linked to various health outcomes in their offspring. Satellite-derived ultraviolet radiation (UVR) data have been used as a proxy for 25(OH)D levels, as individual-level cohort studies are time-consuming, costly and only feasible for common outcomes. ...

        Research

        Type 1 Diabetes

        A lifelong auto-immune condition that can affect anyone, but is most commonly diagnosed in childhood. ...

        Research

        The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva

        We have developed an LC-MS/MS assay that accurately measures saliva 25(OH)D3 levels, which correlated with serum levels ...

        Research

        Use of Continuous Glucose Monitoring Trends to Facilitate Exercise in Children with Type 1 Diabetes

        This study investigated the use of a carbohydrate intake algorithm based on continuous glucose monitoring trends during physical activity ...

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