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        Fetal head circumference growth in children with specific language impairment

        The aim was to characterise fetal brain growth in children with specific language impairment (SLI). A nested case-control study was set in Perth, WA. ...

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        ART, birth defects and subfertility-what should prospective patients be told?

        Clinicians who counsel prospective ART patients about birth defect risk should provide information about the overall risk of having a child with a birth defect ...

        Research

        Two newly identified cat allergens: The von Ebner gland protein Fel d 7 and the latherin-like protein Fel d 8

        Characterization of the complete IgE binding spectrum of cat allergens is important for the development of improved diagnosis and effective immunotherapeutics. ...

        Research

        An investigation of parental mental health among the Aboriginal population in Western Australia, and its impact on children’s outcomes

        Carrington Fiona Shepherd Stanley CCJ FJ PhD FAA FASSA MSc MD FFPHM FAFPHM FRACP FRANZCOG HonDSc HonDUniv HonFRACGP HonMD HonFRCPCH HonLLB (honoris causa) Honorary Research Associate Patron 08 6319 1176 contact@telethonkids.org.au Honorary Research ...

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        Multigenerational disadvantage in Australia

        Francis Steve Mitrou Zubrick FG SR BEc FASSA, FAAMHS, MSc AM PhD Program Head, Population Health, and Team Head, Human Development and Community Wellbeing Honorary Emeritus Research Fellow 08 6319 1499 08 6319 1409 francis.mitrou@telethonkids.org.au ...

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        Mechanisms of IgE sensitization

        Pat Deborah Holt Strickland PG DH PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic Program Patrick.Holt@telethonkids.org.au Deb.Strickland@telethonkids.org.au Emeritus Honorary ...

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        Early treatment with fluvoxamine, bromhexine, cyproheptadine, and niclosamide to prevent clinical deterioration in patients with symptomatic COVID-19: a randomized clinical trial

        Repurposed drugs with host-directed antiviral and immunomodulatory properties have shown promise in the treatment of COVID-19, but few trials have studied combinations of these agents. The aim of this trial was to assess the effectiveness of affordable, widely available, repurposed drugs used in combination for treatment of COVID-19, which may be particularly relevant to low-resource countries.  ...

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        Conceptualising Wellbeing for Australian Aboriginal LGBTQA+ Young People

        It is likely that young people who are both Aboriginal and Torres Strait Islander and LGBTQA+ would be at increased risk for poor mental health outcomes due to the layered impacts of discrimination they experience; however, there is very little empirical evidence focused on the mental health and wellbeing of Aboriginal and Torres Strait Islander LGBTQA+ young people. The current study represents a qualitative exploration of wellbeing among Aboriginal LGBTQA+ young people.  ...

        Research

        Gender-Neutral Toilets: A Qualitative Exploration of Inclusive School Environments for Sexuality and Gender Diverse Youth in Western Australia

        School toilets have been identified by sexuality and gender diverse (SGD) students as the least safe spaces in educational institutions. They are sites of verbal, physical and sexual victimisation. ...

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        Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming

        We recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target to fetal conventional dendritic cell (cDC) progenitors. Here, we profile maternal OM-85 treatment-associated transcriptomic signatures in fetal bone marrow, and identify a series of immunometabolic pathways which provide essential metabolites for accelerated myelopoiesis. ...

        Research

        Children of parents who have been hospitalised with psychiatric disorders are at risk of poor school readiness

        Children of parents who have been hospitalised with psychiatric disorders are at risk for poor school readiness ...

        Research

        The school experiences of children and adolescents with type 1 diabetes in Western Australia

        Elevated levels of emotional difficulties among school students with T1D and variable levels of support from school staff to assist these students to manage their diabetes at school ...

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