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        PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

        Our findings present a novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis ...

        Research

        Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome

        IgG3 levels and proportions of IgG3 (%IgG) in serum at CIS diagnosis were inversely correlated with the time until conversion to MS ...

        Research

        Tryptophan and arginine catabolic enzymes and regulatory cytokines in clinically isolated syndrome and multiple sclerosis

        Higher IDO and ARG expression in clinically isolated syndrome and multiple sclerosis provides one sustained homeostatic mechanism to control multiple sclerosis-associated inflammation ...

        Research

        Early life innate immune signatures of persistent food allergy

        Early life innate immune dysfunction may represent a key immunological driver and predictor of persistent food allergy in childhood ...

        Research

        Cochrane corner: hearing aids for mild to moderate hearing loss in adults

        The evidence supports the widespread provision of hearing aids as the first-line clinical management for those seeking help for hearing difficulties ...

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        Structure-function relationships of the neisserial EptA enzyme responsible for phosphoethanolamine decoration of lipid A: Rationale for drug targeting

        This review concentrates on the phosphoethanolamine decoration of lipid A in the pathogenic species of the genus Neisseria ...

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        Airway function in infancy is linked to airflow measurements and respiratory symptoms from childhood into adulthood

        Lung airflow measurements track from birth into early adulthood, suggesting a permanent and stable airway framework is laid down in the antenatal period ...

        Research

        Active surveillance of 2017 seasonal influenza vaccine safety: An observational cohort study of individuals aged 6 months and older in Australia

        AusVaxSafety surveillance demonstrated comparable and expected safety outcomes for the 2017 quadrivalent inactivated influenza vaccine brands used in Australia ...

        Research

        Investigating falls in adults with intellectual disability living in community settings and their experiences of post-fall care services

        This study will determine the rate of falls among older adults with ID living in community based settings, which will assist to identify the extent of this problem ...

        Research

        No relationship between autistic traits and salivary testosterone concentrations in men from the general population

        The current data add to the increasing evidence for the lack of relationship between autistic traits and postnatal levels of testosterone in men ...

        Research

        Antibiotics versus topical antiseptics for chronic suppurative otitis media

        To assess the effectiveness of antibiotics versus antiseptics for people with chronic suppurative otitis media. ...

        Research

        Cardiometabolic risk factors at 5 years after omega-3 fatty acid supplementation in infancy

        Supplementation with n-3 LCPUFA in infancy revealed a reduction in waist circumference at 5 years ...

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