Convenient, readily available and helping create a close and loving bond between baby and mother, breastfeeding is highly regarded for optimising infant health and preventing chronic disease in adulthood. ...

• Telethon Kids Institute
• Our research
• Research Topics

Whole genome sequencing of poor and exceptional survivors identified a gain in Chromosome 19 that was exclusive to the exceptional survivors ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

Early changes in cell morphology upon treatments are a strong indication that the inhibitor is directly targeting tubulin ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

Both tumour suppressive and oncogenic functions have been reported for dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Herein, we performed a detailed investigation to delineate the role of DYRK1A in glioblastoma. Our phosphoproteomic and mechanistic studies show that DYRK1A induces degradation of cyclin B by phosphorylating CDC23, which is necessary for the function of the anaphase-promoting complex, a ubiquitin ligase that degrades mitotic proteins. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

This study highlights the importance of human milk in providing anti-severe acute respiratory syndrome coronavirus 2 immunity to newborns. The highest protective activity of human milk against COVID-19 was found in colostrum from infected mothers. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• June 2024

We investigated the effects of cause of death (COVID-19 with an underlying medical condition vs. without) and prolonged grief disorder status (PGD present or absent) on participants' reported public stigma towards the bereaved. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• June 2024

Childhood obesity creates a predisposition to develop adult hypertension and diabetes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

The current study sought to further investigate in 91 English-speaking typically developing children and 30 children with specific language impairment... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• February 2012

We discovered a previously unknown major resistance mechanism in glioma in that most EGFR domain III-targeting antibodies do not neutralize EGFRvIII ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at the Telethon Institute in 2005 and is now a Senior Research ...

• Telethon Kids Institute
• Projects

Alison McDonnell AM BSc (Hons), PhD Early Career Fellow alison.mcdonnell@telethonkids.org.au Early Career Fellow Dr Alison McDonnell is a post-doctoral scientist with a research focus in cancer immunology. Following a PhD using preclinical models of ...

• Telethon Kids Institute
• Projects

Terrance W. Joost Ben Johns Lesterhuis Wylie T WJL BW BSc PhD Honorary Research Associate Program Head, Cancer; Chronic and Severe Diseases RFA Deputy Head Senior Research Fellow Joost.Lesterhuis@telethonkids.org.au ben.wylie@telethonkids.org.au ...

• Telethon Kids Institute
• Projects