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        Modelling evolutionary pathways for commensalism and hypervirulence in neisseria meningitidis

        Neisseria meningitidis, the meningococcus, resides exclusively in humans and causes invasive meningococcal disease (IMD). The population of N. meningitidis is structured into stable clonal complexes by limited horizontal recombination in this naturally transformable species. ...

        Research

        A Survey of Infectious Diseases and Microbiology Clinicians in Australia and New Zealand About the Management of Staphylococcus aureus Bacteremia

        Significant variation in practice, particularly for patients with a severe disease phenotype and antibiotic-resistant profile ...

        Research

        The impact of influenza infection on young children, their family and the health care system

        Influenza infection in young children has a significant impact on medication use, absenteeism and the use of health care service ...

        Research

        The Great Recession and Children’s Mental Health in Australia

        This paper analyzes the effects of “shocks” to community-level unemployment expectations, induced by the Great Recession, on children’s mental well-being ...

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        Targeting the bone marrow microenvironment: a novel therapeutic strategy for pre-B acute lymphoblastic leukemia

        Our findings shed light on the mechanisms of leukemia-induced bone loss ...

        Research

        Atypical nested 22q11.2 duplications are associated with neurodevelopmental phenotypes including autism spectrum disorder with incomplete penetrance

        Our findings contribute to the genotype–phenotype data for atypical nested 22q11.2 duplications, with implications for genetic counseling ...

        Research

        Challenges in Accurately Assessing Prenatal Alcohol Exposure in a Study of Fetal Alcohol Spectrum Disorder in a Youth Detention Center

        Accurately assessing prenatal alcohol consumption is exceptionally challenging when assessed retrospectively as part of a FASD assessment for a young person sentenced to detention ...

        Research

        Nicotine and other potentially harmful compounds in "nicotine-free" e-cigarette liquids in Australia

        The aim of our investigation was to assess the chemical composition of a range of e-liquids available in Australia, focusing on nicotine and other potentially harmful compounds ...

        Research

        Risks and obstacles in implementing a public health approach to the wellbeing and protection of children

        We have also been engaged with and excited by the attempts to adopt a public health approach to the care and protection of children as described throughout this book ...

        Research

        Emerging diabetes and metabolic conditions among Aboriginal and Torres Strait Islander young people

        Collaboration between clinicians and researchers is required to establish the prevalence and disease burden of type 2 diabetes among Indigenous young people ...

        Research

        Allergy alerts — The incidence of parentally reported allergies in children presenting for general anesthesia

        Only the minority of parent-reported allergies in pediatric surgical patients were specialist confirmed and likely to be clinically relevant ...

        Research

        The dystroglycan receptor maintains glioma stem cells in the vascular niche

        These findings reveal a central role of the DG receptor, not only as a structural element, but also as a critical factor promoting mesenchymal-like GBM ...

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