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        2197-2208 of 3501 results for 'development'

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        Insights into respiratory disease through bioinformatics

        Here, we review the basic concepts in bioinformatics and genomic data analysis and illustrate the application of these tools to further our understanding of lung diseases ...

        Research

        Maternal Smoking During Pregnancy Induces Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic Risk

        This study demonstrates a critical timing of cigarette smoke exposure over the life course for establishing persistent changes in DNA methylation into adolescence ...

        Research

        Why do Victims become Perpetrators of Peer Bullying? Moral Disengagement in the Cycle of Violence

        Previous studies have shown that there is overlap between victimization and the perpetration of bullying, and social and motivational variables are known to mediate this relationship. However, the effects of different moral disengagement strategies have not been studied, despite the fact that they exert a major influence on aggressive behavior. ...

        Research

        Study protocol for a randomised controlled trial evaluating the effect of folic acid supplementation beyond the first trimester on maternal plasma unmetabolised folic acid in late gestation

        Taking folic acid containing supplements prior to and during early pregnancy reduces the risk of neural tube defects. Neural tube defects occur prior to 28 days postconception, after which, there is no proven benefit of continuing to take folic acid. However, many women continue to take folic acid containing supplements throughout the pregnancy. ...

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        PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo

        Our results reveal long-lasting changes to progenitor cells of monocytes/macrophages by a 2-hour dimethyl PGE2 pulse that, in turn, limits the migration of their daughter cells to chemoattractants and inflammatory mediators. ...

        Research

        Paediatric antimicrobial stewardship and safe prescribing: An assessment of medical staff knowledge and behaviour

        Participants demonstrated a good understanding of safe prescribing and antimicrobial stewardship ...

        Research

        Effects of maltreatment and parental schizophrenia spectrum disorders on early childhood social-emotional functioning: a population record linkage study

        We used data from a large Australian population to determine the independent and moderating effects of maltreatment and parental SSDs on early childhood. ...

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        A pilot study to develop assessment tools for Group A Streptococcus surveillance studies

        Group A Streptococcus (GAS) causes pharyngitis (sore throat) and impetigo (skin sores) GAS pharyngitis triggers rheumatic fever (RF) with epidemiological evidence supporting that GAS impetigo may also trigger RF in Australian Aboriginal children. Understanding the concurrent burden of these superficial GAS infections is critical to RF prevention. This pilot study aimed to trial tools for concurrent surveillance of sore throats and skins sore for contemporary studies of RF pathogenesis including development of a sore throat checklist for Aboriginal families and pharynx photography. ...

        Research

        Intention to Engage in Alcohol Use during Pregnancy: The Role of Attitudes and Prototypes

        There is no known risk-free level of alcohol use in pregnancy. Despite this, many still believe that occasional drinking is safe. To-date, there is limited evidence of the influences on women's decisions about low to moderate alcohol use in pregnancy. ...

        Research

        Estimated dietary intake of polyphenols from cereal foods and associated lifestyle and demographic factors in the Melbourne Collaborative Cohort Study

        Cereal foods are consumed globally and are important sources of polyphenols with potential health benefits, yet dietary intakes are unclear. We aimed to calculate the dietary intakes of polyphenols from cereal foods in the Melbourne Collaborative Cohort Study, and describe intakes by demographic and lifestyle factors. ...

        Research

        Well-being and Distress in University Students with ADHD Traits: the Mediating Roles of Self-Compassion and Emotion Regulation Difficulties

        Tertiary education is particularly demanding for students with attention-deficit hyperactivity disorder (ADHD), who often struggle with emotion regulation and are at greater risk of internalising disorders compared to their peers. Self-compassion is a skill associated with positive mental health and adaptive emotion regulation that might support students in managing the emotional challenges of studying with ADHD. ...

        Research

        Histo-blood group antigen profile of Australian Aboriginal children and seropositivity following oral rotavirus vaccination

        Histo-blood group antigens (HBGAs) may influence immune responses to rotavirus vaccination. ...

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