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        217-228 of 521 results for 'Growth'

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        Tissue resident memory T cells: putting cancer cells to sleep and a target for therapy

        Alison McDonnell AM BSc (Hons), PhD Early Career Fellow alison.mcdonnell@telethonkids.org.au Early Career Fellow Dr Alison McDonnell is a post-doctoral scientist with a research focus in cancer immunology. Following a PhD using preclinical models of ...

        Research

        Clinical Trials in the Brain Tumour Population: Challenges and Strategies for the Future

        This review identifies challenges and barriers to successful development of drugs in neuro-oncology trials at the preclinical, clinical and translational stages that we believe has contributed to poor outcomes for patients over the last 30 years. ...

        Research

        Simultaneous Targeting of DNA Replication and Homologous Recombination in Glioblastoma with a Polyether Ionophore

        Our findings highlight the potential of salinomycin to induce DNA lesions and inhibit homologous recombination to greatly enhance the effect of radiotherapy ...

        Research

        Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams

        While maternal high fat diet compromised litter survival, it also promoted somatic and lung growth (increased lung volume) in the offspring ...

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        PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

        A novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis ...

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        Fine mapping under linkage peaks for symptomatic or asymptomatic outcomes of Leishmania infantum infection in Brazil

        The transforming growth factor-beta pathway is important in the immunopathogenesis of Visceral leishmaniasis ...

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        Lung function changes in children exposed to mine fire smoke in infancy

        Chronic, low-intensity air pollution exposure has been consistently associated with reduced lung function throughout childhood. However, there is limited research regarding the implications of acute, high-intensity air pollution exposure. We aimed to determine whether there were any associations between early life exposure to such an episode and lung growth trajectories. ...

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        Overcoming challenges in measuring early childhood development across cultures

        These challenges in measuring early childhood development are exacerbated when making comparisons across cultures ...

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        Group A Streptococcus co-ordinates manganese import and iron efflux in response to hydrogen peroxide stress

        Here, we demonstrate that group A Streptococcus (GAS) utilises Mn(II) import via MtsABC during conditions of hydrogen peroxide stress ...

        Research

        Developing evidence-based recommendations for optimal interpregnancy intervals in high-income countries: Protocol for an international cohort study

        We aim to assess the impact of interpregnancy intervals on maternal and child health outcomes in high-income countries ...

        Research

        Developmental respiratory physiology

        Various developmental aspects of respiratory physiology put infants and young children at an increased risk of respiratory failure, which is associated with a higher rate of critical incidents during anesthesia. ...

        Research

        What we know about suicide prevention for Aboriginal and Torres Strait Islander peoples

        This fact sheet addresses what we currently know about suicide prevention for Aboriginal and Torres Strait Islander peoples. ...

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